Gentob
Generic Name
gentob-03-eye-ointment
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| gentob 03 eye ointment | ৳ 80.00 | N/A |
Description
Overview of the medicine
Gentob-03 Eye Ointment is an antibiotic preparation used to treat various bacterial infections of the eye, such as conjunctivitis, blepharitis, and keratitis.
Uses & Indications
Dosage
Adults
Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac of the affected eye(s) 2-3 times daily, or as directed by physician.
Elderly
Same as adult dosage. No specific dose adjustment required.
Renal_impairment
Not applicable for ophthalmic use due to minimal systemic absorption.
How to Take
For ophthalmic use only. Gently pull down the lower eyelid to create a small pouch, apply a thin strip of ointment, and close the eye briefly. Avoid touching the applicator tip to the eye or any surface.
Mechanism of Action
The active ingredient, likely Tobramycin, inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to cell death.
Pharmacokinetics
Onset
Rapid onset of action, typically within hours of application.
Excretion
Primarily excreted unchanged by the kidneys if systemically absorbed, but local effects are predominant.
Half life
Systemic half-life is not clinically relevant for ophthalmic use due to negligible systemic absorption.
Absorption
Minimal systemic absorption occurs following ophthalmic administration, resulting in high local concentrations.
Metabolism
Not significantly metabolized systemically when applied topically to the eye.
Side Effects
Contraindications
- Hypersensitivity to tobramycin or any other component of the formulation.
- Known allergy to other aminoglycoside antibiotics.
Drug Interactions
Other Ophthalmic Preparations
If using more than one ophthalmic medication, allow at least 5 minutes between applications. Ointments should be applied last.
Storage
Store below 25°C. Do not freeze. Keep away from light and moisture. Keep out of reach of children.
Overdose
Ophthalmic overdose is unlikely. If excessive amount is applied, rinse the eye(s) with lukewarm water. No specific antidote is available.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Minimal systemic absorption suggests low risk to fetus. For lactation, it is unknown whether topical ophthalmic tobramycin is excreted in human milk, but systemic exposure is low.
Side Effects
Contraindications
- Hypersensitivity to tobramycin or any other component of the formulation.
- Known allergy to other aminoglycoside antibiotics.
Drug Interactions
Other Ophthalmic Preparations
If using more than one ophthalmic medication, allow at least 5 minutes between applications. Ointments should be applied last.
Storage
Store below 25°C. Do not freeze. Keep away from light and moisture. Keep out of reach of children.
Overdose
Ophthalmic overdose is unlikely. If excessive amount is applied, rinse the eye(s) with lukewarm water. No specific antidote is available.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Minimal systemic absorption suggests low risk to fetus. For lactation, it is unknown whether topical ophthalmic tobramycin is excreted in human milk, but systemic exposure is low.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date; discard 1 month after opening.
Availability
Pharmacies, Hospitals
Approval Status
DGDA Approved
Patent Status
Generic/Off-patent
WHO Essential Medicine
YesClinical Trials
Studies typically demonstrate efficacy in bacterial ocular infections with a good safety profile, similar to other tobramycin ophthalmic preparations.
Lab Monitoring
- No specific lab monitoring is typically required for ophthalmic tobramycin.
Doctor Notes
- Emphasize correct application technique to minimize contamination and ensure effective drug delivery.
- Monitor patients for signs of superinfection (e.g., fungal) or allergic reactions, especially with prolonged use.
- Advise patients not to share the medication to prevent cross-contamination.
Patient Guidelines
- Wash hands thoroughly before and after applying the ointment.
- Do not share your eye ointment with others.
- Avoid touching the applicator tip to your eye or any other surface to prevent contamination.
- Remove contact lenses before application and wait at least 15 minutes before reinserting them.
- Use the ointment for the full prescribed duration, even if symptoms improve, to prevent recurrence.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose.
Driving Precautions
This ointment may cause temporary blurred vision immediately after application. Exercise caution when driving or operating machinery until vision clears.
Lifestyle Advice
- Maintain good eye hygiene to prevent further infection.
- Avoid rubbing your eyes.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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