Glysup
Generic Name
Glycerin Suppository
Manufacturer
Various manufacturers
Country
Global
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| glysup 230 gm suppository | ৳ 5.02 | N/A |
Description
Overview of the medicine
Glysup 230 mg Suppository is a hyperosmotic laxative used for the short-term relief of occasional constipation, particularly in infants and young children. It works by drawing water into the intestines to soften stool and promote bowel movement.
Uses & Indications
Dosage
Adults
Not typically used for adults; adult formulations are usually 1.5-3 g.
Elderly
Not typically used for elderly; adult formulations are usually 1.5-3 g.
Renal_impairment
No special dosage adjustment required due to minimal systemic absorption.
How to Take
For rectal use only. Insert one suppository into the rectum, pointed end first. For infants (230mg strength): typically one suppository once daily as needed. It should be retained for 15-60 minutes or until the urge to defecate is strong. Wash hands before and after use.
Mechanism of Action
Glycerin acts as a hyperosmotic agent, drawing water into the colon from surrounding tissues, which softens the stool and increases stool bulk. It also has a local irritant effect on the rectal mucosa, stimulating peristalsis and promoting bowel movement. Additionally, it lubricates the stool, making passage easier.
Pharmacokinetics
Onset
15-60 minutes
Excretion
Primarily eliminated in feces as unabsorbed drug; small absorbed amounts are excreted renally.
Half life
Not clinically relevant due to minimal systemic absorption.
Absorption
Minimally absorbed systemically when administered rectally.
Metabolism
Small absorbed amounts are metabolized in the liver to carbon dioxide and water or glycogen.
Side Effects
Contraindications
- Hypersensitivity to glycerin
- Abdominal pain of unknown origin
- Appendicitis
- Intestinal obstruction
- Rectal bleeding
Drug Interactions
Storage
Store below 30°C in a cool, dry place. Protect from heat and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely with rectal administration. Excessive use may lead to diarrhea, abdominal cramping, and electrolyte imbalance. Discontinue use and consult a doctor if severe symptoms occur.
Pregnancy & Lactation
Generally considered safe for occasional use during pregnancy and lactation, but consult a healthcare professional before use.
Side Effects
Contraindications
- Hypersensitivity to glycerin
- Abdominal pain of unknown origin
- Appendicitis
- Intestinal obstruction
- Rectal bleeding
Drug Interactions
Storage
Store below 30°C in a cool, dry place. Protect from heat and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely with rectal administration. Excessive use may lead to diarrhea, abdominal cramping, and electrolyte imbalance. Discontinue use and consult a doctor if severe symptoms occur.
Pregnancy & Lactation
Generally considered safe for occasional use during pregnancy and lactation, but consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, supermarkets
Approval Status
Generally Recognized As Safe and Effective (GRASE)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Glycerin suppositories are well-established, and extensive clinical trials for efficacy and safety were conducted historically for this generic formulation rather than ongoing studies.
Lab Monitoring
- Not typically required
Doctor Notes
- Advise patients on proper administration technique.
- Caution against prolonged use without medical supervision, especially in infants.
- Emphasize lifestyle modifications for long-term constipation relief.
Patient Guidelines
- Do not use for more than one week unless directed by a doctor.
- Ensure proper hydration for effective stool softening.
- Consult a doctor if constipation persists or worsens.
Missed Dose Advice
Not applicable for an 'as needed' medication for constipation. Use as directed when needed.
Driving Precautions
No known effects on ability to drive or operate machinery.
Lifestyle Advice
- Maintain a high-fiber diet.
- Drink plenty of fluids.
- Engage in regular physical activity.
- Establish a regular bowel routine.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Glysup Brand
Other medicines available under the same brand name
