Hexiscrub
Generic Name
Chlorhexidine Gluconate
Manufacturer
ACI Pharmaceuticals (example)
Country
Bangladesh (example)
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Description
Overview of the medicine
Hexiscrub is an antiseptic and disinfectant solution containing chlorhexidine gluconate, used for surgical hand scrubbing, pre-operative skin preparation, and general skin disinfection.
Uses & Indications
Dosage
Adults
For surgical hand scrub: Wet hands and forearms with water, apply 5ml of Hexiscrub, scrub for 3 minutes, rinse, apply another 5ml, scrub for 3 minutes, then rinse thoroughly. For skin preparation: Apply undiluted to the treatment area, rub thoroughly for at least 2 minutes, then allow to air dry.
Elderly
No specific dosage adjustments required.
Renal_impairment
No specific dosage adjustments required.
How to Take
For external use only. Do not swallow. Avoid contact with eyes, ears, and mouth. If contact occurs, rinse immediately with plenty of water.
Mechanism of Action
Chlorhexidine gluconate is a biguanide antiseptic that binds to the bacterial cell wall and disrupts the cell membrane, leading to increased permeability, leakage of intracellular components, and ultimately cell death. It has broad-spectrum activity against Gram-positive and Gram-negative bacteria, yeasts, and some viruses.
Pharmacokinetics
Onset
Rapid onset of action, typically within 30 seconds to 1 minute.
Excretion
Excreted mainly via feces if systemically absorbed, but topical application leads to negligible systemic exposure.
Half life
Not relevant for systemic half-life due to minimal absorption; prolonged residual activity on skin.
Absorption
Very poorly absorbed through intact skin. Systemic absorption after topical application is minimal.
Metabolism
Minimal systemic metabolism, if any, due to poor absorption.
Side Effects
Contraindications
- Hypersensitivity to chlorhexidine gluconate or any components of the formulation.
- Should not be used for meninges or in the middle ear.
Drug Interactions
Soaps and other anionic agents
May neutralize the antiseptic effect of chlorhexidine.
Storage
Store below 30°C. Protect from light. Do not freeze.
Overdose
Topical overdose may lead to skin irritation. Accidental ingestion may cause gastrointestinal irritation; seek medical attention.
Pregnancy & Lactation
Considered safe for topical use during pregnancy and lactation due to minimal systemic absorption. Consult a healthcare professional before use.
Side Effects
Contraindications
- Hypersensitivity to chlorhexidine gluconate or any components of the formulation.
- Should not be used for meninges or in the middle ear.
Drug Interactions
Soaps and other anionic agents
May neutralize the antiseptic effect of chlorhexidine.
Storage
Store below 30°C. Protect from light. Do not freeze.
Overdose
Topical overdose may lead to skin irritation. Accidental ingestion may cause gastrointestinal irritation; seek medical attention.
Pregnancy & Lactation
Considered safe for topical use during pregnancy and lactation due to minimal systemic absorption. Consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved for topical antiseptic use
Patent Status
Patent expired, widely available as generic
WHO Essential Medicine
YesClinical Trials
Extensively studied and clinically proven for its antiseptic efficacy in various surgical and healthcare settings.
Lab Monitoring
- Not applicable for topical use.
Doctor Notes
- Ensure proper contact time for maximum efficacy.
- Not for injection or internal use.
- Monitor for signs of allergic reactions, especially in patients with known sensitivities.
Patient Guidelines
- For external use only.
- Avoid contact with eyes, ears, mouth, and other mucous membranes.
- Do not use on open wounds, broken skin, or sensitive areas unless directed by a doctor.
- Discontinue use if irritation or allergic reaction occurs.
- Keep out of reach of children.
Missed Dose Advice
Not applicable as it's used as needed for disinfection.
Driving Precautions
Does not affect ability to drive or operate machinery.
Lifestyle Advice
- Maintain good hygiene practices in conjunction with antiseptic use.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Hexiscrub Brand
Other medicines available under the same brand name
