Hyginol
Generic Name
Chlorhexidine Gluconate Solution
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| hyginol 03 3 solution | ৳ 17.00 | N/A |
Description
Overview of the medicine
Hyginol 0.3% Solution contains Chlorhexidine Gluconate, a broad-spectrum antiseptic agent used for skin disinfection, wound cleansing, and general hygiene. It helps to kill bacteria, viruses, and fungi, preventing infections.
Uses & Indications
Dosage
Adults
Apply undiluted to the affected skin area 2-3 times daily or as directed by a healthcare professional. For wound cleansing, gently apply to the wound. For pre-operative skin prep, follow standard protocols.
Elderly
No specific dosage adjustment required; use as per adult dosage.
Renal_impairment
No dosage adjustment required as systemic absorption is minimal.
How to Take
Ensure the affected area is clean. Apply a small amount of solution directly to the skin or wound using a sterile swab or cotton ball. Allow to air dry. Do not rinse off.
Mechanism of Action
Chlorhexidine Gluconate is a cationic biguanide that binds to the negatively charged bacterial cell wall, altering its permeability. This leads to leakage of intracellular components and ultimately bacterial cell death. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, some viruses, and fungi.
Pharmacokinetics
Onset
Rapid, within seconds to minutes of application.
Excretion
Mostly eliminated via feces if ingested, minimal renal excretion for absorbed amounts.
Half life
Not relevant for topical application due to minimal systemic absorption.
Absorption
Minimal systemic absorption through intact skin. Absorption increases with damaged skin, but remains generally low.
Metabolism
Not extensively metabolized systemically due to poor absorption.
Side Effects
Contraindications
- Hypersensitivity to Chlorhexidine Gluconate or any components of the solution.
- Should not be used in contact with brain, meninges, or middle ear.
- Avoid use on extensive burn areas.
Drug Interactions
Povidone-iodine
Can be used sequentially but avoid simultaneous application without thorough rinsing.
Soaps and anionic agents
Inactivated by soaps and other anionic compounds. Ensure complete rinsing of soap residues before applying Hyginol solution.
Storage
Store below 30°C in a dry place, away from direct sunlight and heat. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to minimal absorption. Excessive topical application may lead to skin irritation. If ingested, seek medical attention. Symptoms may include gastrointestinal upset.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, as systemic absorption is minimal. Consult a doctor if concerned.
Side Effects
Contraindications
- Hypersensitivity to Chlorhexidine Gluconate or any components of the solution.
- Should not be used in contact with brain, meninges, or middle ear.
- Avoid use on extensive burn areas.
Drug Interactions
Povidone-iodine
Can be used sequentially but avoid simultaneous application without thorough rinsing.
Soaps and anionic agents
Inactivated by soaps and other anionic compounds. Ensure complete rinsing of soap residues before applying Hyginol solution.
Storage
Store below 30°C in a dry place, away from direct sunlight and heat. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to minimal absorption. Excessive topical application may lead to skin irritation. If ingested, seek medical attention. Symptoms may include gastrointestinal upset.
Pregnancy & Lactation
Generally considered safe for topical use during pregnancy and lactation, as systemic absorption is minimal. Consult a doctor if concerned.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Pharmacies, hospitals, clinics, general stores
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Chlorhexidine Gluconate has been extensively studied and is a well-established antiseptic with numerous clinical trials supporting its efficacy and safety for skin disinfection and wound care over decades.
Lab Monitoring
- No routine laboratory monitoring is required for topical use.
Doctor Notes
- Emphasize external use only and warn against accidental ingestion.
- Advise patients to report any signs of allergic reactions immediately.
- Check for known hypersensitivity to chlorhexidine before recommending.
Patient Guidelines
- For external use only. Do not ingest.
- Avoid contact with eyes, ears, and mucous membranes. If contact occurs, rinse thoroughly with water.
- Do not use on large areas of skin or for prolonged periods without medical advice.
- Discontinue use if irritation or allergic reaction occurs and consult a doctor.
Missed Dose Advice
As this is a topical solution used on an as-needed basis or as per a schedule for treatment, if a dose is missed, apply it as soon as you remember. Do not apply extra to compensate.
Driving Precautions
Hyginol 0.3% Solution is for topical use and has no known effect on the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good personal hygiene to prevent infections.
- Keep wounds clean and covered when appropriate.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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