Hysomide
Generic Name
Hysosemide 10 mg Tablet
Manufacturer
MedPro Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| hysomide 10 mg tablet | ৳ 6.90 | ৳ 69.00 |
Description
Overview of the medicine
Hysomide 10 mg tablet is a potent loop diuretic used to treat edema associated with congestive heart failure, renal disease, and hepatic cirrhosis, as well as hypertension.
Uses & Indications
Dosage
Adults
For edema: Initially 10-20 mg once daily, adjusted based on response. For hypertension: 5-10 mg once daily.
Elderly
Start with a lower dose and monitor closely.
Renal_impairment
Dosage adjustment may be necessary; monitor electrolyte levels.
How to Take
Take orally, with or without food, preferably in the morning to avoid nocturia.
Mechanism of Action
Blocks sodium and chloride reabsorption in the ascending limb of the loop of Henle, leading to increased excretion of water, sodium, chloride, potassium, and hydrogen ions.
Pharmacokinetics
Onset
Typically within 30-60 minutes after oral administration.
Excretion
Primarily via the kidneys through both glomerular filtration and tubular secretion.
Half life
Approximately 1-2 hours, but can be prolonged in renal impairment.
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Limited hepatic metabolism; mainly excreted unchanged.
Side Effects
Contraindications
- •Hypersensitivity to Hysosemide or sulfonamides
- •Anuria
- •Severe electrolyte depletion
- •Hepatic coma
Drug Interactions
NSAIDs
May reduce diuretic effect and increase risk of nephrotoxicity.
Digoxin
Increased risk of digoxin toxicity due to hypokalemia.
Lithium
Reduced renal clearance of lithium, leading to increased lithium levels.
Aminoglycoside antibiotics
Increased risk of ototoxicity.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include dehydration, electrolyte imbalance, hypotension. Management involves fluid and electrolyte replacement, and supportive care.
Pregnancy & Lactation
Use only if clearly needed and potential benefits outweigh risks. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies and hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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