Take orally, preferably with food or milk to minimize gastrointestinal upset. Do not exceed recommended dose.

Ibuprofen works by inhibiting the synthesis of prostaglandins, which are chemicals in the body responsible for pain, fever, and inflammation. It achieves this by blocking the cyclooxygenase (COX-1 and COX-2) enzymes.

• •Hypersensitivity to ibuprofen or other NSAIDs
• •Active gastrointestinal bleeding or peptic ulcer
• •Severe renal or hepatic impairment
• •Severe heart failure
• •Third trimester of pregnancy

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.

Symptoms include nausea, vomiting, abdominal pain, lethargy, dizziness, tinnitus, headache, and nystagmus. Severe overdose can lead to GI bleeding, renal failure, hypotension, respiratory depression, and coma. Treatment is supportive, including gastric lavage or activated charcoal if recent ingestion.

Avoid in the third trimester of pregnancy due to risk of premature closure of ductus arteriosus. Use with caution in first and second trimesters only if clearly needed. Small amounts excreted in breast milk; generally considered compatible with breastfeeding at low doses.