Ipralin
Generic Name
Ipratropium Bromide
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ipralin 100 mcg inhaler | ৳ 250.00 | N/A |
| ipralin 25 mg respirator solution | ৳ 20.00 | N/A |
Description
Overview of the medicine
Ipralin (Ipratropium Bromide) is an anticholinergic bronchodilator used for the maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Uses & Indications
Dosage
Adults
Usually 2 puffs (40 mcg) four times a day, not exceeding 12 puffs in 24 hours.
Elderly
No specific dose adjustment is required, but caution is advised.
Renal_impairment
No dose adjustment needed, as systemic absorption is minimal.
How to Take
For oral inhalation only. Shake well before use. Prime the inhaler before first use or if not used for a long time.
Mechanism of Action
Ipratropium bromide is an anticholinergic (parasympatholytic) agent which, by local action, inhibits vagally mediated reflexes by antagonizing the action of acetylcholine at the muscarinic receptors on bronchial smooth muscle. This results in bronchodilation.
Pharmacokinetics
Onset
Within 15 minutes
Excretion
Mainly excreted in faeces (unabsorbed drug) and urine (absorbed drug/metabolites).
Half life
Approximately 1.6 hours (terminal half-life of absorbed drug)
Absorption
Poorly absorbed systemically following oral inhalation. Less than 20% of the dose reaches the lower airways, and a small portion is absorbed into systemic circulation.
Metabolism
Hydrolyzed to inactive metabolites via esterases.
Side Effects
Contraindications
- •Hypersensitivity to Ipratropium Bromide, atropine, or its derivatives
- •Acute bronchospasm where rapid response is required
Drug Interactions
Beta-adrenergics
May enhance bronchodilator effect.
Other anticholinergics
Increased anticholinergic effects.
Storage
Store below 30°C. Protect from freezing and direct sunlight. Do not puncture or incinerate canister.
Overdose
Symptoms include dry mouth, blurred vision, and tachycardia. Treatment is supportive and symptomatic.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed during pregnancy. Excretion into human milk is unknown, use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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