Isovent
Generic Name
isovent-600-mcg-tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| isovent 600 mcg tablet | ৳ 40.13 | ৳ 40.13 |
Description
Overview of the medicine
Isovent 600 mcg tablet contains salbutamol, a short-acting beta-2 adrenergic agonist used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD).
Uses & Indications
Dosage
Adults
Typically, 2-4 mg (2000-4000 mcg) orally 3-4 times daily. For a 600 mcg tablet, the dosage regimen should be determined by a physician.
Elderly
Lower doses may be required. Consult a physician.
Renal_impairment
No specific dose adjustment is generally required, but caution is advised in severe impairment.
How to Take
Take orally with water, with or without food. Follow your doctor's instructions.
Mechanism of Action
Salbutamol selectively stimulates beta-2 adrenergic receptors in the bronchial smooth muscle, leading to bronchodilation and relief of bronchospasm.
Pharmacokinetics
Onset
30 minutes (oral)
Excretion
Mainly excreted in urine as unchanged drug and metabolites.
Half life
3.8 to 6 hours
Absorption
Well absorbed from the gastrointestinal tract after oral administration. Peak plasma concentrations are achieved within 2-3 hours.
Metabolism
Undergoes hepatic metabolism, primarily by conjugation to salbutamol 4'-O-sulfate.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the formulation
- Cardiac arrhythmias associated with tachycardia
- Severe heart disease
Drug Interactions
Diuretics
May lead to hypokalemia, especially with high doses of salbutamol.
Beta-blockers
May reduce the bronchodilator effect of salbutamol and cause severe bronchospasm.
MAO inhibitors and Tricyclic Antidepressants
May potentiate the cardiovascular effects of salbutamol.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, palpitations, and hypokalemia. Treatment is supportive, and a beta-blocker may be used with caution.
Pregnancy & Lactation
Use with caution. Benefit-risk assessment by a physician is necessary. Salbutamol is excreted in breast milk.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the formulation
- Cardiac arrhythmias associated with tachycardia
- Severe heart disease
Drug Interactions
Diuretics
May lead to hypokalemia, especially with high doses of salbutamol.
Beta-blockers
May reduce the bronchodilator effect of salbutamol and cause severe bronchospasm.
MAO inhibitors and Tricyclic Antidepressants
May potentiate the cardiovascular effects of salbutamol.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, palpitations, and hypokalemia. Treatment is supportive, and a beta-blocker may be used with caution.
Pregnancy & Lactation
Use with caution. Benefit-risk assessment by a physician is necessary. Salbutamol is excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies
Approval Status
Approved
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensively studied for safety and efficacy in respiratory conditions. Ongoing research for new formulations.
Lab Monitoring
- Serum potassium levels (especially in severe asthma or concomitant use of diuretics)
Doctor Notes
- Advise patients on proper use and potential side effects.
- Monitor for cardiovascular effects, especially in patients with pre-existing conditions.
- Educate on differentiating rescue medication from maintenance therapy.
Patient Guidelines
- Do not exceed the prescribed dose.
- Seek immediate medical attention if breathing difficulties worsen.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume regular dosing. Do not double the dose.
Driving Precautions
May cause dizziness or tremors. Exercise caution when driving or operating machinery.
Lifestyle Advice
- Avoid smoking.
- Maintain a healthy lifestyle and diet.
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