Ivertin
Generic Name
Ivermectin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ivtin 12 mg tablet | ৳ 20.00 | ৳ 200.00 |
Description
Overview of the medicine
Ivertin 12 mg tablet contains Ivermectin, an antiparasitic medication used to treat certain parasitic infections in humans, including onchocerciasis, strongyloidiasis, and scabies.
Uses & Indications
Dosage
Adults
Typical dose for strongyloidiasis is a single oral dose of 200 mcg/kg body weight. For onchocerciasis, 150 mcg/kg body weight as a single oral dose, repeated every 3 to 12 months. For scabies, a single oral dose of 200 mcg/kg body weight, potentially repeated after 7-14 days.
Elderly
Dosage considerations are generally similar to adults, but caution is advised due to potential decreased hepatic, renal, or cardiac function, and concomitant disease or other drug therapy.
Renal_impairment
No specific dosage adjustment recommended for mild to moderate renal impairment. Use with caution in severe renal impairment.
How to Take
Take orally with water on an empty stomach (at least 1 hour before or 2 hours after a meal) for optimal absorption. Tablets can be crushed if necessary for easier administration.
Mechanism of Action
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells. This binding leads to an increase in the permeability of the cell membrane to chloride ions, causing hyperpolarization of the nerve or muscle cell, and results in paralysis and death of the parasite.
Pharmacokinetics
Onset
Effects typically observed within days for parasitic infections.
Excretion
Mainly excreted in feces (virtually exclusively), with less than 1% excreted in urine.
Half life
Approximately 12-36 hours.
Absorption
Well absorbed orally; peak plasma concentrations reached approximately 4-6 hours post-dose.
Metabolism
Extensively metabolized in the liver, primarily by CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to Ivermectin or any component of the tablet
- Pregnancy (unless potential benefits outweigh risks)
- Lactation (for some indications)
Drug Interactions
Warfarin
May enhance anticoagulant effect, increasing risk of bleeding. Monitor INR.
CNS depressants (e.g., benzodiazepines, barbiturates)
May potentiate CNS depression.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms of overdose may include rash, edema, headache, dizziness, nausea, vomiting, abdominal pain, diarrhea, seizures, and coma. Treatment is symptomatic and supportive, including fluid and electrolyte replacement, respiratory support, and blood pressure control.
Pregnancy & Lactation
Pregnancy: Category C. Use only if the potential benefit justifies the potential risk to the fetus. Lactation: Ivermectin is excreted in human milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Side Effects
Contraindications
- Hypersensitivity to Ivermectin or any component of the tablet
- Pregnancy (unless potential benefits outweigh risks)
- Lactation (for some indications)
Drug Interactions
Warfarin
May enhance anticoagulant effect, increasing risk of bleeding. Monitor INR.
CNS depressants (e.g., benzodiazepines, barbiturates)
May potentiate CNS depression.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms of overdose may include rash, edema, headache, dizziness, nausea, vomiting, abdominal pain, diarrhea, seizures, and coma. Treatment is symptomatic and supportive, including fluid and electrolyte replacement, respiratory support, and blood pressure control.
Pregnancy & Lactation
Pregnancy: Category C. Use only if the potential benefit justifies the potential risk to the fetus. Lactation: Ivermectin is excreted in human milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by drug regulatory authorities (e.g., FDA for some uses, DGDA in Bangladesh)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established Ivermectin's efficacy and safety for approved parasitic indications. Ongoing research explores its potential in other areas, including some viral infections, but these uses are generally not recommended outside of controlled studies.
Lab Monitoring
- No routine laboratory monitoring is typically required, but liver function tests may be considered in patients with pre-existing hepatic impairment or prolonged use.
Doctor Notes
- Verify diagnosis of parasitic infection before prescribing.
- Educate patients on proper administration and potential side effects.
- Counsel patients against self-medication and unapproved uses.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Swallow the tablet whole with water on an empty stomach.
- Do not take more than the recommended dose.
Missed Dose Advice
Since Ivermectin is often taken as a single dose or short course, missing a dose means the full treatment might be compromised. Contact your doctor or pharmacist for advice.
Driving Precautions
May cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how the medicine affects you.
Lifestyle Advice
- Maintain good hygiene to prevent reinfection.
- Follow up with your doctor as advised to ensure complete eradication of the parasite.
- Report any unusual or severe side effects immediately.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Ivertin Brand
Other medicines available under the same brand name
