Joytrip
Generic Name
Methylcobalamin
Manufacturer
MediCo Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| joytrip 150 mcg chewable tablet | ৳ 5.02 | ৳ 50.20 |
Description
Overview of the medicine
Joytrip 150 mcg Chewable Tablet is a vitamin B12 supplement containing Methylcobalamin, essential for nerve tissue health, brain function, and red blood cell production. It helps prevent and treat vitamin B12 deficiency.
Uses & Indications
Dosage
Adults
Typically 1 chewable tablet once daily, or as directed by a healthcare professional.
Elderly
Same as adult dosage, or adjusted based on individual needs and deficiency level.
Renal_impairment
No specific dose adjustment required for mild to moderate renal impairment. Consult physician for severe cases.
How to Take
Chew the tablet thoroughly before swallowing, or allow it to dissolve slowly in the mouth. Can be taken with or without food.
Mechanism of Action
Methylcobalamin acts as a coenzyme in several metabolic pathways, including the metabolism of fats and carbohydrates, and the synthesis of protein. It is crucial for the formation of red blood cells and the maintenance of a healthy nervous system. Specifically, it is involved in the synthesis of methionine from homocysteine and the isomerization of methylmalonyl-CoA to succinyl-CoA.
Pharmacokinetics
Onset
Effects are gradual, typically noticeable over weeks to months of regular supplementation.
Excretion
Primarily through urine, with excess rapidly excreted. Some enterohepatic recirculation occurs.
Half life
Variable, ranges from a few days to weeks depending on tissue stores and excretion.
Absorption
Well absorbed from the gastrointestinal tract, primarily in the ileum. Absorption can be enhanced by intrinsic factor.
Metabolism
Converted to active coenzyme forms (methylcobalamin and adenosylcobalamin) in the body.
Side Effects
Contraindications
- •Hypersensitivity to Methylcobalamin or any component of the formulation
- •Leber's disease (due to risk of optic nerve atrophy with B12 treatment)
Drug Interactions
Chloramphenicol
May reduce the hematological response to vitamin B12.
Colchicine, Neomycin, Aminosalicylic acid
May decrease vitamin B12 absorption.
H2-blockers, Proton Pump Inhibitors (PPIs)
May reduce vitamin B12 absorption over long-term use.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Vitamin B12 is water-soluble, and excess is generally excreted. Overdose is rare and not associated with severe toxicity. Management is supportive.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation at recommended doses, as B12 is essential for fetal development and breast milk. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date
Availability
Pharmacies, supermarkets, online stores
Approval Status
Approved by health authorities
Patent Status
Generic/Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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