Kidizinc
Generic Name
Zinc Sulphate Monohydrate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| kidizinc 10 mg syrup | ৳ 35.00 | N/A |
Description
Overview of the medicine
Kidizinc is an oral zinc supplement used to treat and prevent zinc deficiency, especially in children, and as an adjunct therapy for acute diarrhea.
Uses & Indications
Dosage
Adults
Adults: 20-50 mg elemental zinc daily, depending on deficiency severity.
Elderly
Elderly: Similar to adult dosage, with careful monitoring for renal impairment.
Renal_impairment
Renal impairment: Dosage adjustment may be required; consult a physician.
How to Take
Administer orally, preferably with meals to minimize gastric upset, though food may slightly decrease absorption. Can be mixed with water or breast milk for infants.
Mechanism of Action
Zinc is an essential trace element vital for numerous biological processes including immune function, cell division, wound healing, and proper growth and development. It acts as a cofactor for over 300 enzymes.
Pharmacokinetics
Onset
Therapeutic effects may be observed within hours to days, particularly for acute conditions like diarrhea.
Excretion
Excreted primarily via feces, with smaller amounts through urine and sweat.
Half life
The biological half-life of zinc in the body is long, estimated around 280 days.
Absorption
Absorption occurs mainly in the small intestine. Bioavailability can be affected by dietary factors.
Metabolism
Zinc is not extensively metabolized; it is utilized by various tissues and enzymes throughout the body.
Side Effects
Contraindications
- Hypersensitivity to zinc or any components of the formulation.
Drug Interactions
Penicillamine
Zinc may reduce the absorption of penicillamine.
Iron supplements
High doses of iron may reduce zinc absorption. Take zinc at a different time of day.
Tetracyclines (e.g., Doxycycline)
Zinc may decrease the absorption of tetracyclines. Take zinc at least 2 hours before or 4-6 hours after tetracyclines.
Fluoroquinolones (e.g., Ciprofloxacin)
Zinc may decrease the absorption of fluoroquinolones. Take zinc at least 2 hours before or 4-6 hours after fluoroquinolones.
Storage
Store below 30°C in a dry place, protected from light. Keep out of reach of children.
Overdose
Symptoms of acute zinc overdose include nausea, vomiting, abdominal pain, diarrhea, and dizziness. Chronic overdose can lead to copper deficiency and anemia. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Zinc is an essential nutrient during pregnancy and lactation. It is generally considered safe when taken at recommended daily allowances. Consult a doctor for specific dosages.
Side Effects
Contraindications
- Hypersensitivity to zinc or any components of the formulation.
Drug Interactions
Penicillamine
Zinc may reduce the absorption of penicillamine.
Iron supplements
High doses of iron may reduce zinc absorption. Take zinc at a different time of day.
Tetracyclines (e.g., Doxycycline)
Zinc may decrease the absorption of tetracyclines. Take zinc at least 2 hours before or 4-6 hours after tetracyclines.
Fluoroquinolones (e.g., Ciprofloxacin)
Zinc may decrease the absorption of fluoroquinolones. Take zinc at least 2 hours before or 4-6 hours after fluoroquinolones.
Storage
Store below 30°C in a dry place, protected from light. Keep out of reach of children.
Overdose
Symptoms of acute zinc overdose include nausea, vomiting, abdominal pain, diarrhea, and dizziness. Chronic overdose can lead to copper deficiency and anemia. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Zinc is an essential nutrient during pregnancy and lactation. It is generally considered safe when taken at recommended daily allowances. Consult a doctor for specific dosages.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture.
Availability
Available in all pharmacies and drugstores
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials support the efficacy of zinc supplementation in reducing the duration and severity of diarrhea in children and for addressing zinc deficiency.
Lab Monitoring
- Serum zinc levels (if deficiency suspected or monitoring treatment)
- Serum copper levels (with long-term high dose zinc supplementation)
Doctor Notes
- Crucial for pediatric diarrhea management as per WHO guidelines.
- Monitor for signs of copper deficiency in prolonged high-dose use.
- Advise patients on proper administration with meals.
Patient Guidelines
- Take exactly as directed by your doctor or pharmacist.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. Do not double the dose to catch up.
Driving Precautions
Does not typically affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in essential nutrients.
- Adequate hydration is important, especially during diarrhea.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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