Klabid
Generic Name
Clarithromycin 125 mg/5 ml Suspension
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| klabid 125 mg suspension | ৳ 390.00 | N/A |
Description
Overview of the medicine
Klabid 125 mg Suspension is an antibiotic from the macrolide class, used to treat various bacterial infections in children.
Uses & Indications
Dosage
Adults
Not typically used for adults in this suspension form; adults usually take tablets.
Elderly
Not typically used for elderly in this suspension form; elderly usually take tablets with caution for renal impairment.
Renal_impairment
Dosage adjustment may be required; consult physician.
How to Take
Administer orally, with or without food. Shake well before use. Do not refrigerate after reconstitution.
Mechanism of Action
Clarithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
Pharmacokinetics
Onset
Onset of action is typically within hours.
Excretion
Excreted via urine and feces.
Half life
Approximately 3-7 hours for clarithromycin, depending on the dose.
Absorption
Well absorbed from the gastrointestinal tract, food delays but does not affect the extent of absorption.
Metabolism
Extensively metabolized in the liver to 14-hydroxyclarithromycin (active metabolite) and other inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to clarithromycin or other macrolide antibiotics
- •Concomitant use with cisapride, pimozide, astemizole, terfenadine, ergotamine, dihydroergotamine, or HMG-CoA reductase inhibitors (statins) that are extensively metabolized by CYP3A4
- •Severe hepatic impairment in combination with renal impairment
Drug Interactions
Digoxin
Increased digoxin levels, monitor levels.
Warfarin
May potentiate anticoagulant effects, monitor INR.
Oral contraceptives
May reduce efficacy of hormonal contraceptives.
Statins (e.g., simvastatin, lovastatin)
Increased risk of myopathy, rhabdomyolysis.
Storage
Store dry powder below 30°C, protected from light and moisture. Do not refrigerate. Keep out of reach of children.
Overdose
Symptoms may include gastrointestinal discomfort (nausea, vomiting, diarrhea, abdominal pain). Treatment is symptomatic and supportive; gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Clarithromycin is excreted in breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2 years for dry powder; 14 days after reconstitution when stored at room temperature.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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