Laxol
Generic Name
Macrogol 3350 (Polyethylene Glycol 3350)
Manufacturer
Renata Limited
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| laxol 335 gm oral solution | ৳ 136.00 | N/A |
Description
Overview of the medicine
Laxol contains Macrogol 3350, an osmotic laxative used for the symptomatic treatment of constipation. It works by increasing the water content in the stool, making it softer and easier to pass.
Uses & Indications
Dosage
Adults
1 sachet (13.8g) dissolved in 125ml of water, once daily, preferably in the morning. Dosage can be adjusted to 2-3 sachets daily if needed.
Elderly
Same as adults, but consider starting with a lower dose.
Renal_impairment
No dose adjustment is required for patients with renal impairment.
How to Take
Dissolve the contents of one sachet in 125ml of water. Stir well until the powder is completely dissolved, then drink immediately. May be taken with or without food.
Mechanism of Action
Macrogol 3350 acts by retaining water in the intestinal lumen, leading to increased stool volume and softened consistency. This facilitates bowel movements without causing significant electrolyte imbalances.
Pharmacokinetics
Onset
Onset of action typically occurs within 24 to 48 hours.
Excretion
Excreted unchanged in the feces.
Half life
Not applicable due to minimal systemic absorption.
Absorption
Minimally absorbed from the gastrointestinal tract.
Metabolism
Not metabolized by intestinal microflora or human enzymes.
Side Effects
Contraindications
- •Intestinal obstruction or perforation
- •Severe inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis, toxic megacolon)
- •Hypersensitivity to the active substance or any excipient
Drug Interactions
Oral medications
May reduce the absorption of other orally administered medicinal products taken simultaneously. It is advisable to take other medications at least one hour before or after Macrogol 3350.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Overdose may lead to diarrhea, abdominal pain, and vomiting. Treatment involves discontinuing the medication and correcting any fluid or electrolyte imbalances.
Pregnancy & Lactation
Macrogol 3350 is generally considered safe during pregnancy and lactation due to minimal systemic absorption. However, consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Pharmacies, drugstores
Approval Status
Approved
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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