laxopic
Generic Name
Sodium Picosulfate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| laxopic 5 mg oral solution | ৳ 85.00 | N/A |
Description
Overview of the medicine
Laxopic 5 mg Oral Solution is a stimulant laxative used for the short-term relief of occasional constipation. It works by stimulating the bowel muscles to increase their activity and promote a bowel movement.
Uses & Indications
Dosage
Adults
Usually 5-10 mg (10-20 drops) orally once daily at bedtime.
Elderly
Similar to adults, but consider lowest effective dose initially.
Renal_impairment
No specific adjustment usually needed for mild to moderate renal impairment; use with caution in severe cases.
How to Take
Take orally as directed, usually at night before bedtime. It typically produces a bowel movement within 6-12 hours. Ensure adequate fluid intake.
Mechanism of Action
Sodium picosulfate is an orally administered laxative that is hydrolyzed by colonic bacteria to form active compounds (e.g., bis-(p-hydroxyphenyl)-pyridyl-2-methane). These active metabolites act directly on the colonic mucosa, stimulating peristalsis and inhibiting water and electrolyte absorption, leading to increased water content in the stool and facilitation of defecation.
Pharmacokinetics
Onset
6-12 hours
Excretion
Primarily in feces, some renal excretion of glucuronides.
Half life
Short for parent compound; active metabolite half-life varies.
Absorption
Poorly absorbed from the gastrointestinal tract.
Metabolism
Hydrolyzed by colonic bacteria to active metabolite (bis-(p-hydroxyphenyl)-pyridyl-2-methane).
Side Effects
Contraindications
- •Acute abdominal pain
- •Intestinal obstruction
- •Acute inflammatory bowel disease (e.g., appendicitis, ulcerative colitis)
- •Severe dehydration
- •Undiagnosed abdominal pain
Drug Interactions
Antibiotics
Antibiotics may reduce the efficacy of sodium picosulfate by altering gut flora.
Diuretics/Corticosteroids
Concurrent use may increase the risk of electrolyte imbalance.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose may lead to abdominal cramps, diarrhea, and significant fluid and electrolyte loss. Management involves supportive care; electrolyte levels may need monitoring.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and advised by a physician. Discuss potential risks with your doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years (product-specific, check label)
Availability
Pharmacies, hospitals
Approval Status
Approved by health authorities
Patent Status
Patent expired, generic available
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Global Brand Names
International brand names for this medicine
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