Laxur Plus
Generic Name
Lactulose + Ispaghula Husk
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| laxur plus 40 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Laxur Plus is a combination laxative containing Lactulose and Ispaghula Husk, used for the treatment of chronic constipation and conditions requiring soft stools.
Uses & Indications
Dosage
Adults
Typically 1-2 sachets (10g lactulose + 3.5g isphaghula) once daily, mixed with water. Dose may be adjusted based on response.
Elderly
Same as adult dosage, with careful monitoring for fluid and electrolyte balance.
Renal_impairment
No specific dose adjustment required, but monitor fluid intake.
How to Take
Mix the contents of one sachet with a full glass of water (approx. 150 ml). Stir well and drink immediately. Ensure adequate fluid intake throughout the day.
Mechanism of Action
Lactulose works as an osmotic laxative, drawing water into the colon to soften stools. Ispaghula Husk is a bulk-forming laxative, absorbing water and swelling to form a gel-like mass that promotes bowel movement.
Pharmacokinetics
Onset
1-3 days for full effect (for Lactulose).
Excretion
Lactulose is excreted unchanged or as bacterial metabolites in feces. Ispaghula Husk is excreted unchanged in feces.
Half life
Not applicable due to minimal absorption.
Absorption
Lactulose is poorly absorbed from the gastrointestinal tract. Ispaghula Husk is not absorbed.
Metabolism
Lactulose is metabolized by colonic bacteria. Ispaghula Husk is not metabolized.
Side Effects
Contraindications
- Hypersensitivity to Lactulose or Ispaghula Husk
- Galactosaemia
- Intestinal obstruction
- Acute abdominal pain of unknown origin
Drug Interactions
Antacids
May reduce the effect of Lactulose.
Other laxatives
Avoid concomitant use as it may lead to severe diarrhea and electrolyte imbalance.
Broad-spectrum antibiotics
May reduce the degradation of Lactulose by colonic bacteria, potentially reducing its efficacy.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Overdose may lead to diarrhea, abdominal pain, and electrolyte disturbances (especially hypokalemia). Management involves symptomatic treatment and correction of fluid/electrolyte imbalance.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation, but use with caution and under medical advice. Ensure adequate fluid intake.
Side Effects
Contraindications
- Hypersensitivity to Lactulose or Ispaghula Husk
- Galactosaemia
- Intestinal obstruction
- Acute abdominal pain of unknown origin
Drug Interactions
Antacids
May reduce the effect of Lactulose.
Other laxatives
Avoid concomitant use as it may lead to severe diarrhea and electrolyte imbalance.
Broad-spectrum antibiotics
May reduce the degradation of Lactulose by colonic bacteria, potentially reducing its efficacy.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Overdose may lead to diarrhea, abdominal pain, and electrolyte disturbances (especially hypokalemia). Management involves symptomatic treatment and correction of fluid/electrolyte imbalance.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation, but use with caution and under medical advice. Ensure adequate fluid intake.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Combination products of lactulose and psyllium husk have demonstrated efficacy and safety in clinical trials for chronic constipation.
Lab Monitoring
- Monitor serum electrolytes (especially potassium) with prolonged use or in patients susceptible to electrolyte imbalances.
- Monitor blood glucose levels in diabetic patients due to lactulose content.
Doctor Notes
- Advise patients to drink plenty of water with each dose and throughout the day.
- Caution in diabetic patients due to lactulose content; monitor blood glucose.
- Not for immediate relief of acute constipation.
- Educate on the importance of diet and lifestyle changes.
Patient Guidelines
- Always mix the granules thoroughly with a full glass of water and drink immediately.
- Maintain adequate fluid intake throughout the day to prevent the risk of choking and ensure efficacy.
- Do not chew or crush the granules.
- Take consistently at the same time each day for best results.
- Consult a doctor if constipation persists for more than 7 days.
Missed Dose Advice
If a dose is missed, take it as soon as you remember, unless it is almost time for your next dose. Do not take a double dose to make up for a forgotten one.
Driving Precautions
Laxur Plus is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Increase dietary fiber intake (fruits, vegetables, whole grains).
- Engage in regular physical activity.
- Ensure adequate hydration by drinking plenty of water.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.