Limpet
Generic Name
Limpet 2 mg Tablet
Manufacturer
Inventa Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| limpet 2 mg tablet | ৳ 7.00 | ৳ 98.00 |
Description
Overview of the medicine
Limpet 2 mg Tablet contains Limpet, a selective serotonin reuptake inhibitor (SSRI) used for the treatment of major depressive disorder, generalized anxiety disorder, and panic disorder. It works by increasing the levels of serotonin in the brain, a natural substance that helps maintain mental balance.
Uses & Indications
Dosage
Adults
Initial dose: 2 mg once daily. May be increased to 4 mg after one week, if needed. Maximum recommended dose is 8 mg daily.
Elderly
Initial dose: 1 mg once daily. Max dose typically 4 mg daily, with caution.
Renal_impairment
No dose adjustment needed for mild to moderate impairment. Use with caution in severe impairment.
How to Take
Take orally, once daily, with or without food. Swallow the tablet whole with water; do not crush or chew.
Mechanism of Action
Limpet selectively inhibits the reuptake of serotonin (5-HT) into the presynaptic neuron, thereby increasing the concentration of 5-HT in the synaptic cleft. This leads to enhanced serotonergic neurotransmission, which is believed to be responsible for its antidepressant and anxiolytic effects.
Pharmacokinetics
Onset
Therapeutic effects may begin within 1-2 weeks, but full effect may take 4-6 weeks.
Excretion
Excreted predominantly in the urine (60%) and feces (40%) as metabolites.
Half life
Approximately 24-30 hours, allowing for once-daily dosing.
Absorption
Well absorbed orally, with peak plasma concentrations achieved within 4-6 hours.
Metabolism
Extensively metabolized in the liver, primarily by CYP2C19 and CYP3A4 enzymes.
Side Effects
Contraindications
- Hypersensitivity to Limpet or any components of the tablet.
- Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing MAOIs.
- Uncontrolled narrow-angle glaucoma.
Drug Interactions
MAOIs
Concomitant use is contraindicated due to risk of serotonin syndrome.
NSAIDs
Increased risk of gastrointestinal bleeding.
Triptans
Increased risk of serotonin syndrome.
Warfarin
May increase bleeding risk. Monitor INR.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, nausea, vomiting, dizziness, tachycardia, tremor, and rarely, serotonin syndrome. Treatment is symptomatic and supportive, including maintaining a clear airway and monitoring vital signs. Gastric lavage and activated charcoal may be considered soon after ingestion.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Small amounts may be excreted in breast milk; caution advised. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to Limpet or any components of the tablet.
- Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing MAOIs.
- Uncontrolled narrow-angle glaucoma.
Drug Interactions
MAOIs
Concomitant use is contraindicated due to risk of serotonin syndrome.
NSAIDs
Increased risk of gastrointestinal bleeding.
Triptans
Increased risk of serotonin syndrome.
Warfarin
May increase bleeding risk. Monitor INR.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, nausea, vomiting, dizziness, tachycardia, tremor, and rarely, serotonin syndrome. Treatment is symptomatic and supportive, including maintaining a clear airway and monitoring vital signs. Gastric lavage and activated charcoal may be considered soon after ingestion.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Small amounts may be excreted in breast milk; caution advised. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by regulatory authorities (e.g., DGDA)
Patent Status
Patent protected
Clinical Trials
Limpet has undergone extensive Phase I, Phase II, and Phase III clinical trials demonstrating efficacy and safety in its approved indications. Further post-marketing surveillance is ongoing.
Lab Monitoring
- No routine lab monitoring is generally required. However, liver and renal function tests may be considered at baseline and periodically in patients with pre-existing impairment.
- Monitor serum sodium levels, especially in elderly patients or those taking diuretics.
Doctor Notes
- Initiate Limpet treatment with a low dose and gradually titrate upwards based on patient response and tolerability.
- Monitor patients closely for suicidality, especially at the beginning of treatment or following dose adjustments.
- Advise patients about the potential for withdrawal symptoms if Limpet is discontinued abruptly.
Patient Guidelines
- Do not stop taking Limpet abruptly, as this may lead to withdrawal symptoms. Consult your doctor for gradual dose reduction.
- Report any unusual mood changes, agitation, or suicidal thoughts to your doctor immediately.
- It may take several weeks to feel the full benefits of Limpet. Continue medication as prescribed.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Limpet may cause dizziness, drowsiness, or blurred vision. Avoid driving or operating heavy machinery until you know how this medicine affects you.
Lifestyle Advice
- Maintain a healthy lifestyle with regular exercise and a balanced diet.
- Consider psychotherapy or counseling in conjunction with medication for better outcomes.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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