Lumona
Generic Name
Montelukast
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| lumona 4 mg oral granules | ৳ 8.00 | N/A |
Description
Overview of the medicine
Lumona 4 mg Oral Granules contain Montelukast, a leukotriene receptor antagonist, used for the treatment of asthma and allergic rhinitis in children aged 6 months to 5 years.
Uses & Indications
Dosage
Adults
Adults and adolescents 15 years and older: 10 mg once daily, in the evening. (Note: This is for 10mg tablets, for 4mg granules, typically for younger children).
Elderly
No dosage adjustment necessary for the elderly.
Renal_impairment
No dosage adjustment necessary for patients with renal impairment.
Children_2_5_years
4 mg once daily, in the evening.
Children_6_months_2_years
4 mg once daily, in the evening.
How to Take
Take orally, once daily in the evening, with or without food. The granules can be administered directly into the mouth, dissolved in a teaspoon of cold or room temperature soft food (e.g., applesauce, ice cream, carrots, rice), or mixed with breast milk or formula. Do not open the sachet until ready to use. Do not store mixture for future use.
Mechanism of Action
Montelukast selectively blocks the CysLT1 receptor, thereby inhibiting the physiological actions of leukotriene D4 (LTD4) and other cysteinyl leukotrienes. Cysteinyl leukotrienes are potent inflammatory eicosanoids released from various cells, including mast cells and eosinophils, involved in the pathophysiology of asthma and allergic rhinitis.
Pharmacokinetics
Onset
Within one day for asthma and allergic rhinitis.
Excretion
Primarily excreted in the feces via bile (approximately 86%), with less than 0.2% excreted in urine.
Half life
Plasma half-life ranges from 2.7 to 5.5 hours in healthy adults.
Absorption
Rapidly absorbed after oral administration. Mean oral bioavailability is 64%. Peak plasma concentrations achieved in 2-4 hours.
Metabolism
Extensively metabolized in the liver, primarily by CYP2C8, and to a lesser extent by CYP3A4 and CYP2C9.
Side Effects
Contraindications
- Hypersensitivity to Montelukast or any component of the formulation.
Drug Interactions
Gemfibrozil
May increase montelukast systemic exposure.
Phenobarbital
Decreases montelukast AUC by approximately 40%.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include abdominal pain, somnolence, thirst, headache, vomiting, and psychomotor hyperactivity. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use in pregnancy only if clearly needed and the potential benefit outweighs the potential risk to the fetus. Montelukast is excreted in breast milk; caution should be exercised when administered to a nursing mother.
Side Effects
Contraindications
- Hypersensitivity to Montelukast or any component of the formulation.
Drug Interactions
Gemfibrozil
May increase montelukast systemic exposure.
Phenobarbital
Decreases montelukast AUC by approximately 40%.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include abdominal pain, somnolence, thirst, headache, vomiting, and psychomotor hyperactivity. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use in pregnancy only if clearly needed and the potential benefit outweighs the potential risk to the fetus. Montelukast is excreted in breast milk; caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years, check product packaging for exact date.
Availability
Pharmacies, hospitals
Approval Status
Approved (e.g., FDA, DGDA)
Patent Status
Off-patent
Clinical Trials
Montelukast has been extensively studied in numerous clinical trials demonstrating its efficacy and safety in asthma and allergic rhinitis across various age groups.
Lab Monitoring
- No routine lab monitoring required. Monitor for neuropsychiatric symptoms.
Doctor Notes
- Advise parents/caregivers to be aware of neuropsychiatric symptoms and report them immediately.
- Emphasize that Montelukast is a prophylactic treatment and not for acute relief.
- Educate on proper administration of granules, especially for infants and young children.
Patient Guidelines
- Take this medicine regularly, even if you feel well.
- Do not use this medicine to treat acute asthma attacks.
- Inform your doctor immediately if you experience any neuropsychiatric symptoms.
- Do not abruptly discontinue oral or inhaled corticosteroids when starting Montelukast.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
May cause dizziness or drowsiness in some individuals. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Avoid asthma triggers and allergens.
- Follow up regularly with your healthcare provider for asthma management.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Lumona Brand
Other medicines available under the same brand name
