Merozolyn
Generic Name
Meropenem
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| merozolyn 5 mg tablet | ৳ 25.00 | ৳ 250.00 |
Description
Overview of the medicine
Meropenem is a broad-spectrum carbapenem antibiotic used to treat a wide variety of serious bacterial infections, including those resistant to other antibiotics. It is administered intravenously.
Uses & Indications
Dosage
Adults
500 mg to 1 g IV every 8 hours, depending on infection severity and type.
Elderly
No specific dose adjustment needed unless severe renal impairment.
Renal_impairment
Dose reduction required based on creatinine clearance.
How to Take
Administered intravenously as an infusion over 15-30 minutes or as a bolus injection over 3-5 minutes.
Mechanism of Action
Meropenem is a bactericidal antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs).
Pharmacokinetics
Onset
Rapid
Excretion
Primarily via renal excretion (approximately 70% as unchanged drug).
Half life
Approximately 1 hour
Absorption
Not absorbed orally; administered intravenously.
Metabolism
Minimal hepatic metabolism; primarily metabolized by hydrolysis of beta-lactam ring.
Side Effects
Contraindications
- •Known hypersensitivity to meropenem, other carbapenem antibiotics, or any component of the formulation.
Drug Interactions
Probenecid
Increases plasma concentration and prolongs the half-life of meropenem.
Valproic acid
May decrease valproic acid serum concentrations, leading to loss of seizure control.
Storage
Store below 30°C. Protect from light. Do not freeze.
Overdose
In case of overdose, discontinue meropenem and initiate symptomatic and supportive treatment. Hemodialysis can remove meropenem and its metabolite.
Pregnancy & Lactation
Use in pregnancy only if the potential benefit outweighs the potential risk to the fetus. Meropenem is excreted in breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years, refer to product leaflet for exact duration.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA/FDA
Patent Status
Patent expired for generic Meropenem
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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