Mon
Generic Name
Montelukast 5 mg chewable tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| mon 5 mg chewable tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Montelukast 5 mg chewable tablet is a leukotriene receptor antagonist used for the treatment of asthma and allergic rhinitis in pediatric patients aged 6 to 14 years.
Uses & Indications
Dosage
Adults
This strength (5 mg chewable tablet) is primarily indicated for pediatric patients aged 6 to 14 years. Adults typically take 10 mg tablets. Consult a physician for appropriate adult dosage.
Elderly
No specific dose adjustment required for the elderly for montelukast overall, but this 5 mg chewable tablet strength is not typically for this age group.
Renal_impairment
No dosage adjustment is necessary for patients with renal impairment.
How to Take
Take orally, once daily in the evening, with or without food. Chew the tablet completely before swallowing.
Mechanism of Action
Montelukast selectively antagonizes the cysteinyl leukotriene 1 (CysLT1) receptor, thereby blocking the action of leukotrienes, which are potent inflammatory mediators involved in asthma and allergic rhinitis.
Pharmacokinetics
Onset
Within 1 day for asthma symptoms; benefits for allergic rhinitis may take longer.
Excretion
Primarily excreted in the feces via bile (approximately 86%), with less than 0.2% excreted in urine.
Half life
Approximately 2.7 to 5.5 hours.
Absorption
Rapidly absorbed after oral administration; peak plasma concentrations achieved in 2-4 hours.
Metabolism
Extensively metabolized in the liver by CYP2C8, CYP3A4, and CYP2C9.
Side Effects
Contraindications
- •Hypersensitivity to montelukast or any component of the formulation
- •Acute asthma attacks (not for rescue use)
Drug Interactions
Rifampin
May decrease montelukast plasma concentrations.
Phenobarbital
May decrease montelukast plasma concentrations.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Management involves symptomatic and supportive treatment in case of overdose.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed and potential benefits outweigh risks. Excreted in breast milk, caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the manufacturing date, consult package for exact date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by FDA/DGDA
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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