Moset
Generic Name
Mosapride Citrate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| moset 5 mg syrup | ৳ 25.00 | N/A |
Description
Overview of the medicine
Moset 5 mg Syrup contains Mosapride Citrate, a gastroprokinetic agent used to treat gastrointestinal symptoms such as heartburn, nausea, and vomiting associated with chronic gastritis or functional dyspepsia.
Uses & Indications
Dosage
Adults
Typically 5 mg (5 mL syrup) three times a day, taken orally before meals. Dosage may be adjusted based on symptom severity and patient response.
Elderly
No specific dose adjustment is usually required for elderly patients, but caution is advised due to potential age-related physiological changes. Start with the lowest effective dose.
Renal_impairment
Use with caution in patients with severe renal impairment. Dose adjustment may be necessary. Consult a physician.
How to Take
Moset 5 mg Syrup should be taken orally, typically before meals, three times a day or as directed by your doctor. Use the provided measuring cup or spoon for accurate dosing.
Mechanism of Action
Mosapride selectively acts as a 5-HT4 receptor agonist. By stimulating these receptors, it enhances the release of acetylcholine from enteric neurons, thereby increasing gastrointestinal motility and accelerating gastric emptying.
Pharmacokinetics
Onset
Clinical effects typically observed within 30-60 minutes.
Excretion
Excreted mainly via urine (approximately 75%) and feces (approximately 15%).
Half life
Elimination half-life is approximately 1.5-2 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentration is reached within 1-2 hours.
Metabolism
Extensively metabolized in the liver, primarily by CYP3A4, into inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to mosapride or any component of the formulation.
- •Patients with gastrointestinal hemorrhage, mechanical obstruction, or perforation where increased gastric motility could be harmful.
Drug Interactions
Anticholinergic agents (e.g., Atropine, Scopolamine)
May reduce the prokinetic effect of mosapride.
Azole antifungals (e.g., Ketoconazole, Itraconazole)
May inhibit the metabolism of mosapride, leading to increased plasma levels and potential adverse effects.
Macrolide antibiotics (e.g., Erythromycin, Clarithromycin)
May increase plasma concentrations of mosapride, potentially increasing the risk of side effects. Use with caution.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptomatic and supportive treatment should be initiated. There is no specific antidote for mosapride overdose.
Pregnancy & Lactation
Moset 5 mg Syrup should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as safety in pregnant women has not been established. Exercise caution when administered to a nursing mother, as mosapride may be excreted in breast milk. Consult your doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from the date of manufacture when stored properly.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by health authorities for various gastrointestinal motility disorders
Patent Status
Off-patent
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Global Brand Names
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