Myobac 5 mg tablet should be taken orally with food or milk to minimize gastrointestinal upset. It should be swallowed whole with water, not crushed or chewed. Do not stop taking this medicine abruptly.

Baclofen acts as a GABA-B receptor agonist, particularly at spinal cord level. It inhibits both monosynaptic and polysynaptic reflexes, reducing spasticity and muscle spasms. It hyperpolarizes afferent terminals, inhibiting the release of excitatory amino acids.

• •Hypersensitivity to baclofen or any component of the formulation.
• •Peptic ulcer disease (relative contraindication).
• •Epilepsy not well-controlled by therapy (relative contraindication).

Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose include drowsiness, dizziness, nausea, vomiting, muscle hypotonia, respiratory depression, seizures, and coma. Treatment involves supportive care, gastric lavage if recent ingestion, and respiratory support as needed.

Pregnancy Category C. Baclofen should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk; use with caution in nursing mothers.