Myrica
Generic Name
Myricacin Hydrochloride
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| myrica 25 mg capsule | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Myrica 25 mg capsule is an anxiolytic and hypnotic medication used to treat generalized anxiety disorder and insomnia. It helps to calm the nervous system and promote sleep.
Uses & Indications
Dosage
Adults
Initial dose 25 mg once daily at bedtime for insomnia or 25 mg twice daily for anxiety. May be increased to 50 mg daily based on response.
Elderly
Initial dose 12.5 mg once daily at bedtime, adjust carefully based on response and tolerability.
Renal_impairment
No dose adjustment needed for mild to moderate impairment. Use with caution in severe renal impairment (CrCl < 30 mL/min).
How to Take
Take orally with a glass of water, with or without food. For insomnia, take at bedtime. For anxiety, take as directed by your physician.
Mechanism of Action
Myricacin Hydrochloride acts as a selective serotonin-dopamine modulator (SSDM). It selectively targets specific serotonin and dopamine receptors in the brain, leading to anxiolytic and hypnotic effects without significant sedative side effects associated with traditional benzodiazepines.
Pharmacokinetics
Onset
Within 30-60 minutes for anxiolytic effect, 15-30 minutes for hypnotic effect.
Excretion
Excreted mainly through urine (70%) and feces (30%) as metabolites.
Half life
Approximately 8-10 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract; peak plasma concentration reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver via CYP3A4 enzymes.
Side Effects
Contraindications
- •Hypersensitivity to Myricacin Hydrochloride or any component of the formulation
- •Severe hepatic impairment
- •Acute narrow-angle glaucoma
Drug Interactions
CYP3A4 Inducers (e.g., rifampin, carbamazepine)
May decrease Myricacin plasma levels, reducing efficacy.
CYP3A4 Inhibitors (e.g., ketoconazole, ritonavir)
May increase Myricacin plasma levels, requiring dose adjustment.
CNS Depressants (e.g., alcohol, opioids, other anxiolytics)
Increased sedative effects and respiratory depression.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe drowsiness, confusion, slow reflexes, and breathing difficulties. Treatment is primarily supportive, including airway management, gastric lavage, and administration of activated charcoal. Hemodialysis is not effective.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. Not recommended during breastfeeding as it may pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date
Availability
Available in pharmacies and hospitals nationwide
Approval Status
Approved by DGDA
Patent Status
Patented (Expires 2035)
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in
