Myrica-ER
Generic Name
Standardized Myrica Extract Extended-Release
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| myrica er 330 mg tablet | ৳ 45.00 | ৳ 450.00 |
Description
Overview of the medicine
Myrica-ER 330 mg Tablet contains a standardized extract from the Myrica plant, formulated as an extended-release tablet for sustained therapeutic action. It is primarily used for its anti-inflammatory and digestive support properties, helping to alleviate symptoms associated with various gastrointestinal and inflammatory conditions.
Uses & Indications
Dosage
Adults
One Myrica-ER 330 mg tablet once daily, preferably with a meal.
Elderly
No specific dosage adjustment required for elderly patients, but caution is advised in those with significant hepatic or renal impairment.
Renal_impairment
Use with caution. Dosage adjustment may be necessary in severe renal impairment (eGFR <30 mL/min/1.73m²).
How to Take
Take the tablet whole with a glass of water. Do not crush, chew, or break the tablet as this may affect the extended-release properties.
Mechanism of Action
The exact mechanism is complex and multi-faceted, attributed to various bioactive compounds within the Myrica extract such as flavonoids, tannins, and terpenoids. These compounds are believed to exert anti-inflammatory effects by modulating cytokine production, inhibiting prostaglandin synthesis, and reducing oxidative stress. For digestive support, it may promote healthy gut flora and possess astringent properties that aid in mucosal healing.
Pharmacokinetics
Onset
Within 2-4 hours, with peak effects observed after 6-8 hours.
Excretion
Mainly excreted via urine and feces as metabolites.
Half life
Approximately 10-14 hours (for active metabolites).
Absorption
Slow and sustained absorption over 8-12 hours due to ER formulation, primarily in the small intestine.
Metabolism
Extensively metabolized in the liver via glucuronidation and sulfation pathways.
Side Effects
Contraindications
- Hypersensitivity to Myrica extract or any component of the formulation
- Severe liver disease
- Severe kidney disease
Drug Interactions
CYP450 Substrates
Potentially alter the metabolism of drugs metabolized by CYP enzymes, although clinical significance is unknown.
Anticoagulants/Antiplatelets
May potentiate the effects of blood thinners, increasing risk of bleeding. Monitor INR.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptoms may include exaggerated side effects such as severe gastrointestinal upset, dizziness, or headache. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Insufficient data available on Myrica-ER use during pregnancy and lactation. It should be used only if the potential benefit outweighs the potential risk to the fetus/infant. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to Myrica extract or any component of the formulation
- Severe liver disease
- Severe kidney disease
Drug Interactions
CYP450 Substrates
Potentially alter the metabolism of drugs metabolized by CYP enzymes, although clinical significance is unknown.
Anticoagulants/Antiplatelets
May potentiate the effects of blood thinners, increasing risk of bleeding. Monitor INR.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptoms may include exaggerated side effects such as severe gastrointestinal upset, dizziness, or headache. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Insufficient data available on Myrica-ER use during pregnancy and lactation. It should be used only if the potential benefit outweighs the potential risk to the fetus/infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Proprietary formulation
Clinical Trials
Clinical trials have demonstrated Myrica-ER's efficacy in improving symptoms of IBS and functional dyspepsia, showing good tolerability and a favorable safety profile.
Lab Monitoring
- Liver function tests (LFTs) periodically, especially in patients with pre-existing hepatic conditions.
- Renal function tests if used in patients with kidney impairment.
Doctor Notes
- Advise patients to take Myrica-ER consistently at the same time each day for optimal efficacy.
- Counsel patients on potential interactions with anticoagulants and the importance of reporting any unusual bleeding.
Patient Guidelines
- Follow your doctor's instructions carefully.
- Do not stop taking the medicine without consulting your doctor.
- Inform your doctor about all other medications and supplements you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Myrica-ER is generally not expected to affect the ability to drive or operate machinery. However, if you experience dizziness or any other side effect that impairs your judgment, avoid such activities.
Lifestyle Advice
- Maintain a balanced diet rich in fiber and fluids.
- Engage in regular physical activity to support digestive health.
- Manage stress, as it can impact gastrointestinal function.
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