Nameton
Generic Name
Nameton
Manufacturer
PharmaCorp Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nameton 500 mg tablet | ৳ 15.00 | ৳ 150.00 |
Description
Overview of the medicine
Nameton 500 mg Tablet is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation associated with various conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea.
Uses & Indications
Dosage
Adults
500 mg orally once or twice daily, or as directed by physician. Maximum 1000 mg/day.
Elderly
Lower doses may be required, closely monitor for adverse effects.
Renal_impairment
Use with caution; dose adjustment may be necessary based on creatinine clearance.
How to Take
Take the tablet orally with food or milk to minimize gastrointestinal upset. Swallow whole with water.
Mechanism of Action
Nameton works by inhibiting the activity of cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2. This reduces the production of prostaglandins, which are responsible for pain, inflammation, and fever.
Pharmacokinetics
Onset
Pain relief usually within 30-60 minutes.
Excretion
Excreted mainly via urine as metabolites, with a small portion excreted in feces.
Half life
Approximately 2-4 hours.
Absorption
Well absorbed from the gastrointestinal tract, achieving peak plasma concentrations within 1-2 hours.
Metabolism
Primarily metabolized in the liver by cytochrome P450 enzymes.
Side Effects
Contraindications
- Known hypersensitivity to Nameton or other NSAIDs
- Active peptic ulcer or gastrointestinal bleeding
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
- Coronary Artery Bypass Graft (CABG) surgery
Drug Interactions
SSRIs
Increased risk of gastrointestinal bleeding.
Lithium
Increased plasma lithium levels.
Diuretics
Reduced natriuretic effect and potential for renal impairment.
Methotrexate
Increased methotrexate toxicity.
Anticoagulants
Increased risk of bleeding.
Corticosteroids
Increased risk of gastrointestinal ulceration.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, epigastric pain, lethargy, drowsiness, tinnitus. Severe cases may lead to gastrointestinal bleeding, acute renal failure, coma, convulsions. Management includes supportive and symptomatic measures; gastric lavage and activated charcoal may be considered.
Pregnancy & Lactation
Avoid use during the third trimester of pregnancy due to risk of premature closure of ductus arteriosus. Use with caution during first and second trimesters, only if potential benefits outweigh risks. Not recommended during breastfeeding as it may pass into breast milk.
Side Effects
Contraindications
- Known hypersensitivity to Nameton or other NSAIDs
- Active peptic ulcer or gastrointestinal bleeding
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
- Coronary Artery Bypass Graft (CABG) surgery
Drug Interactions
SSRIs
Increased risk of gastrointestinal bleeding.
Lithium
Increased plasma lithium levels.
Diuretics
Reduced natriuretic effect and potential for renal impairment.
Methotrexate
Increased methotrexate toxicity.
Anticoagulants
Increased risk of bleeding.
Corticosteroids
Increased risk of gastrointestinal ulceration.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, epigastric pain, lethargy, drowsiness, tinnitus. Severe cases may lead to gastrointestinal bleeding, acute renal failure, coma, convulsions. Management includes supportive and symptomatic measures; gastric lavage and activated charcoal may be considered.
Pregnancy & Lactation
Avoid use during the third trimester of pregnancy due to risk of premature closure of ductus arteriosus. Use with caution during first and second trimesters, only if potential benefits outweigh risks. Not recommended during breastfeeding as it may pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Off-patent
Clinical Trials
Clinical trials demonstrated significant efficacy in reducing pain and inflammation compared to placebo, with a comparable safety profile to other NSAIDs. Phase III trials involved over 1000 patients, showing good tolerability.
Lab Monitoring
- Complete Blood Count (CBC)
- Liver Function Tests (LFTs)
- Renal Function Tests (RFTs)
- Blood pressure monitoring
Doctor Notes
- Counsel patients on GI and CV risks associated with NSAID use.
- Consider proton pump inhibitor co-administration in high-risk patients (e.g., history of GI bleeding, elderly, concomitant corticosteroid use).
- Monitor renal function, especially in elderly or those with pre-existing conditions (e.g., heart failure, hypertension).
- Prescribe the lowest effective dose for the shortest possible duration consistent with individual patient treatment goals.
Patient Guidelines
- Do not exceed the recommended dose.
- Take with food to avoid stomach upset.
- Inform your doctor about all other medications you are taking.
- Report any signs of unusual bleeding or stomach pain immediately.
- Avoid alcohol consumption while on this medication.
Missed Dose Advice
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Driving Precautions
Nameton may cause dizziness or drowsiness in some individuals. Avoid driving or operating heavy machinery until you know how this medicine affects you.
Lifestyle Advice
- Maintain adequate hydration.
- Regular exercise may help manage chronic pain conditions.
- Avoid smoking as it increases GI risks.
- Limit excessive caffeine intake.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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