Nandron
Generic Name
Nandrolone Decanoate Injection
Manufacturer
General Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nandron 50 mg injection | ৳ 195.00 | N/A |
Description
Overview of the medicine
Nandrolone Decanoate is an anabolic steroid used for certain medical conditions to promote tissue building processes and reverse catabolism. It belongs to the class of androgens and anabolic steroids.
Uses & Indications
Dosage
Adults
50-100 mg deep intramuscular injection every 3-4 weeks. Dosage should be individualized based on response and adverse effects.
Elderly
Lower doses may be required, and patients should be monitored carefully for adverse effects.
Renal_impairment
Use with caution. Dosage adjustments may be necessary depending on the degree of renal impairment and patient response. Regular monitoring of renal function is advised.
How to Take
Administer as a deep intramuscular injection into the gluteal muscle. Do not administer intravenously.
Mechanism of Action
Nandrolone decanoate binds to androgen receptors in target tissues, leading to stimulation of protein synthesis, increase in muscle mass, and erythropoiesis (red blood cell production). It also has mild androgenic effects.
Pharmacokinetics
Onset
Therapeutic effects may become noticeable within days to weeks of initiation.
Excretion
Excreted mainly in the urine, predominantly as metabolites.
Half life
Approximately 6-12 days (due to the decanoate ester).
Absorption
Slowly absorbed from the intramuscular injection site, providing a prolonged release.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- Known hypersensitivity to nandrolone decanoate or any excipients
- Carcinoma of the prostate or male breast cancer
- Pregnancy and lactation
- Severe liver disease
- Nephrotic syndrome
- Hypercalcaemia
Drug Interactions
Corticosteroids/ACTH
Increased risk of fluid retention and edema.
Insulin and Oral Hypoglycemics
May decrease blood glucose levels, potentially requiring dosage adjustment of antidiabetic agents.
Anticoagulants (e.g., Warfarin)
May enhance anticoagulant effects, requiring reduced anticoagulant dosage and close monitoring of INR.
Storage
Store below 30°C in a cool, dry place, protected from light. Do not freeze.
Overdose
Symptoms of overdose may include virilization in females, acne, fluid retention, or adverse effects on liver function. Treatment is supportive and symptomatic; discontinuation of the drug is usually sufficient. Liver function tests and electrolyte levels should be monitored.
Pregnancy & Lactation
Nandrolone decanoate is contraindicated during pregnancy (Pregnancy Category X) due to the risk of fetal harm, particularly virilization of the female fetus. It is also contraindicated during lactation.
Side Effects
Contraindications
- Known hypersensitivity to nandrolone decanoate or any excipients
- Carcinoma of the prostate or male breast cancer
- Pregnancy and lactation
- Severe liver disease
- Nephrotic syndrome
- Hypercalcaemia
Drug Interactions
Corticosteroids/ACTH
Increased risk of fluid retention and edema.
Insulin and Oral Hypoglycemics
May decrease blood glucose levels, potentially requiring dosage adjustment of antidiabetic agents.
Anticoagulants (e.g., Warfarin)
May enhance anticoagulant effects, requiring reduced anticoagulant dosage and close monitoring of INR.
Storage
Store below 30°C in a cool, dry place, protected from light. Do not freeze.
Overdose
Symptoms of overdose may include virilization in females, acne, fluid retention, or adverse effects on liver function. Treatment is supportive and symptomatic; discontinuation of the drug is usually sufficient. Liver function tests and electrolyte levels should be monitored.
Pregnancy & Lactation
Nandrolone decanoate is contraindicated during pregnancy (Pregnancy Category X) due to the risk of fetal harm, particularly virilization of the female fetus. It is also contraindicated during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Usually 2-3 years from the date of manufacture, specific to the manufacturer's label.
Availability
Available in pharmacies and hospitals
Approval Status
Approved (for specific indications)
Patent Status
Off-patent
Clinical Trials
While Nandrolone Decanoate has been in use for many decades, ongoing clinical trials may explore new indications, optimal dosing regimens, or long-term safety profiles.
Lab Monitoring
- Liver function tests (ALT, AST, bilirubin)
- Lipid profile (cholesterol, triglycerides)
- Hemoglobin and hematocrit levels
- Serum calcium levels
- Prostate-specific antigen (PSA) in males (periodically)
Doctor Notes
- Prescribe with caution, especially in patients with pre-existing cardiac, renal, or hepatic conditions.
- Thorough patient education on risks of abuse and side effects is essential.
- Regular monitoring of laboratory parameters (liver, lipids, blood counts, PSA) is crucial during treatment.
- Consider the potential for psychological dependence and withdrawal symptoms upon discontinuation.
Patient Guidelines
- Do not exceed the prescribed dosage.
- Report any unusual side effects to your doctor immediately.
- Do not use this medicine for non-medical purposes like bodybuilding.
- Regular follow-up appointments and lab tests are crucial.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Nandrolone decanoate is not known to directly impair the ability to drive or operate machinery. However, patients experiencing mood changes or other central nervous system effects should exercise caution.
Lifestyle Advice
- Maintain a balanced diet.
- Engage in regular, moderate exercise as advised by your healthcare provider.
- Avoid alcohol consumption, especially if you have liver issues.
- Inform all healthcare providers about your use of this medicine.
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