Navigo
Generic Name
Saccharomyces boulardii
Manufacturer
General Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| navigo 40 mg injection | ৳ 30,000.00 | N/A |
Description
Overview of the medicine
Navigo is a probiotic preparation containing Saccharomyces boulardii, a yeast used to restore the natural balance of gut flora and manage various forms of diarrhea.
Uses & Indications
Dosage
Adults
1-2 capsules (250-500 mg) once or twice daily, or as directed by physician.
Elderly
Same as adult dosage.
Renal_impairment
No dose adjustment required.
How to Take
Take orally with a glass of water. Capsules can be opened and mixed with food or drink for children or those with difficulty swallowing.
Mechanism of Action
Saccharomyces boulardii acts locally in the gut lumen to restore the intestinal microflora, inhibit the growth of pathogenic bacteria, neutralize bacterial toxins, and enhance local immune response.
Pharmacokinetics
Onset
Effects usually observed within 24-48 hours.
Excretion
Excreted in the feces within 3-5 days after discontinuation.
Half life
Not applicable as it is not systemically absorbed.
Absorption
Not absorbed systemically; acts locally in the gastrointestinal tract.
Metabolism
Not metabolized by the body; remains viable in the gut.
Side Effects
Contraindications
- •Hypersensitivity to Saccharomyces boulardii or any component of the formulation.
- •Immunocompromised patients (e.g., HIV-positive, organ transplant recipients, chemotherapy patients) due to risk of fungemia.
- •Patients with central venous catheters.
Drug Interactions
Antifungal agents
Concomitant use with oral or systemic antifungal agents may reduce the efficacy of Saccharomyces boulardii. Administer at a different time of day.
Storage
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
No specific symptoms of overdose have been reported. High doses may lead to increased flatulence or abdominal discomfort, which typically resolve upon dose reduction or discontinuation.
Pregnancy & Lactation
Saccharomyces boulardii is generally considered safe during pregnancy and lactation. However, consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Off-patent
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Global Brand Names
International brand names for this medicine
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