Nazosol
Generic Name
Oxymetazoline Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nazosol 09 nasal drop | ৳ 25.00 | N/A |
Description
Overview of the medicine
Nazosol is a nasal spray containing Oxymetazoline Hydrochloride, used to relieve nasal congestion due to colds, allergies, and hay fever.
Uses & Indications
Dosage
Adults
2-3 sprays into each nostril every 10-12 hours. Do not exceed 2 doses in 24 hours.
Elderly
Same as adults, or consult physician.
Renal_impairment
No specific dose adjustment required, but consult physician.
How to Take
For nasal use only. Clear the nasal passages before use. Insert nozzle into nostril and spray while inhaling. Do not tilt head back. Avoid contact with eyes.
Mechanism of Action
Oxymetazoline is an alpha-adrenergic agonist that causes vasoconstriction in the nasal mucosa, thereby reducing swelling and congestion.
Pharmacokinetics
Onset
Within minutes (typically 5-10 minutes)
Excretion
Primarily via urine (unaltered drug) and feces.
Half life
Approximately 5-8 hours
Absorption
Minimal systemic absorption from nasal application.
Metabolism
Not extensively metabolized; primarily local action.
Side Effects
Contraindications
- •Hypersensitivity to oxymetazoline or any components.
- •Angle-closure glaucoma.
- •Patients receiving MAO inhibitors or within 14 days of stopping such treatment.
- •Infants under 6 years.
Drug Interactions
Beta-blockers
Reduced hypotensive effects of beta-blockers.
MAO Inhibitors
Can potentiate the pressor effect of oxymetazoline, leading to hypertensive crisis.
Tricyclic Antidepressants
May increase the risk of hypertension.
Storage
Store below 30°C in a dry place, away from light. Do not freeze. Keep the cap tightly closed.
Overdose
Symptoms of overdose include severe drowsiness, sweating, slow heartbeat, coma. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and the benefits outweigh the risks. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years (unopened). Discard 28 days after first opening.
Availability
Pharmacies, drugstores
Approval Status
DGDA approved
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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