Neurobest
Generic Name
Alpha Lipoic Acid
Manufacturer
Apex Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| neurobest 100 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Neurobest 100 mg Tablet contains Alpha Lipoic Acid, a powerful antioxidant that helps protect cells from damage, supports nerve health, and aids in metabolic functions. It is commonly used to manage symptoms of diabetic neuropathy.
Uses & Indications
Dosage
Adults
Typically 100-600 mg daily, divided into 1-3 doses, or as directed by physician.
Elderly
No specific dose adjustment is generally required, but close monitoring is advisable.
Renal_impairment
No specific dose adjustment required, but use with caution in severe impairment.
How to Take
Take with a glass of water, preferably on an empty stomach about 30 minutes before food, or as advised by your doctor. Do not chew or crush the tablet.
Mechanism of Action
Alpha Lipoic Acid acts as a potent antioxidant, neutralizing free radicals and regenerating other antioxidants like Vitamin C, Vitamin E, and glutathione. It improves nerve blood flow, enhances glucose utilization, and may reduce oxidative stress, thereby improving nerve function and reducing neuropathy symptoms.
Pharmacokinetics
Onset
Clinical effects may be observed over several weeks.
Excretion
Primarily excreted via the kidneys as metabolites.
Half life
Approximately 20-50 minutes.
Absorption
Readily absorbed from the gastrointestinal tract, though bioavailability can be reduced by food.
Metabolism
Extensively metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to Alpha Lipoic Acid or any component of the tablet.
Drug Interactions
Antidiabetic agents
Alpha Lipoic Acid may lower blood glucose levels, potentially increasing the risk of hypoglycemia when co-administered with insulin or oral antidiabetic drugs. Blood glucose monitoring is advised.
Chemotherapeutic agents
May interfere with the effectiveness of certain chemotherapeutic drugs (e.g., cisplatin).
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, headache, and in severe cases, seizures or consciousness disturbances. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Limited data are available on its safety in these conditions.
Side Effects
Contraindications
- Hypersensitivity to Alpha Lipoic Acid or any component of the tablet.
Drug Interactions
Antidiabetic agents
Alpha Lipoic Acid may lower blood glucose levels, potentially increasing the risk of hypoglycemia when co-administered with insulin or oral antidiabetic drugs. Blood glucose monitoring is advised.
Chemotherapeutic agents
May interfere with the effectiveness of certain chemotherapeutic drugs (e.g., cisplatin).
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, headache, and in severe cases, seizures or consciousness disturbances. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Limited data are available on its safety in these conditions.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 to 3 years from the date of manufacture.
Availability
Pharmacies, drugstores, online
Approval Status
Approved for general sale (OTC/supplement)
Patent Status
Patent expired; generic available
Clinical Trials
Numerous clinical trials have investigated Alpha Lipoic Acid's efficacy in diabetic neuropathy, showing positive results in reducing symptoms like pain and numbness. Ongoing research explores its role in other neurological disorders and metabolic conditions.
Lab Monitoring
- Blood glucose levels (for diabetic patients)
- Liver function tests (in prolonged use or pre-existing liver conditions)
Doctor Notes
- Advise patients about potential blood glucose lowering effect, especially in diabetics.
- Recommend taking on an empty stomach for optimal absorption.
- Monitor for signs of allergic reactions.
Patient Guidelines
- Take the medicine regularly as prescribed.
- Inform your doctor about all other medications and supplements you are taking.
- Do not stop taking the medicine without consulting your doctor.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Neurobest is generally not known to impair the ability to drive or operate machinery. However, if you experience dizziness or other side effects that affect your concentration, avoid these activities.
Lifestyle Advice
- Maintain a healthy and balanced diet.
- Engage in regular physical activity.
- Avoid excessive alcohol consumption.
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Global Brand Names
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