Nitoxin
Generic Name
Nitoxin 500 mg Tablet
Manufacturer
Global Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| nitoxin 500 mg tablet | ৳ 10.00 | ৳ 60.00 |
Description
Overview of the medicine
Nitoxin 500 mg Tablet is an antibiotic used to treat various bacterial and protozoal infections in different parts of the body.
Uses & Indications
Dosage
Adults
Typically 500 mg orally, 2-3 times daily, for 5-10 days depending on the type and severity of infection.
Elderly
Similar to adult dosage, but dose adjustment may be necessary based on renal or hepatic function.
Renal_impairment
Dose adjustment may be required in severe renal impairment. Consult physician.
How to Take
Take orally with or without food. To minimize gastrointestinal upset, it is often recommended to take with food.
Mechanism of Action
Nitoxin enters bacterial and protozoal cells, where it is reduced to active metabolites. These metabolites damage DNA and inhibit nucleic acid synthesis, leading to cell death.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Mainly excreted in urine, with a smaller portion in feces.
Half life
Approximately 6-8 hours.
Absorption
Rapidly and well absorbed after oral administration. Peak plasma concentrations are achieved within 1-2 hours.
Metabolism
Primarily metabolized in the liver by oxidation and glucuronidation.
Side Effects
Contraindications
- Hypersensitivity to Nitoxin or any component of the formulation
- First trimester of pregnancy (for anaerobic infections)
Drug Interactions
Alcohol
Disulfiram-like reaction (nausea, vomiting, flushing) may occur when consumed with alcohol.
Lithium
May increase serum lithium levels, leading to lithium toxicity.
Warfarin
May enhance the anticoagulant effect of warfarin, increasing the risk of bleeding.
Cimetidine
May prolong the half-life of nitoxin by inhibiting its metabolism.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptomatic and supportive treatment should be provided.
Pregnancy & Lactation
Use during pregnancy only if clearly needed after consulting a doctor. Caution is advised during lactation; potential risks to the infant should be considered.
Side Effects
Contraindications
- Hypersensitivity to Nitoxin or any component of the formulation
- First trimester of pregnancy (for anaerobic infections)
Drug Interactions
Alcohol
Disulfiram-like reaction (nausea, vomiting, flushing) may occur when consumed with alcohol.
Lithium
May increase serum lithium levels, leading to lithium toxicity.
Warfarin
May enhance the anticoagulant effect of warfarin, increasing the risk of bleeding.
Cimetidine
May prolong the half-life of nitoxin by inhibiting its metabolism.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Symptomatic and supportive treatment should be provided.
Pregnancy & Lactation
Use during pregnancy only if clearly needed after consulting a doctor. Caution is advised during lactation; potential risks to the infant should be considered.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture
Availability
Available in pharmacies and hospitals
Approval Status
Approved by local regulatory authorities
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have been conducted to establish the efficacy and safety of Nitoxin in various indications.
Lab Monitoring
- Liver function tests (especially with prolonged therapy or hepatic impairment)
- Complete blood count (with prolonged therapy)
Doctor Notes
- Advise patients to avoid alcohol consumption during and after treatment.
- Monitor liver function, especially in patients with pre-existing hepatic impairment or during prolonged therapy.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor and complete the full course of treatment, even if you feel better.
- Avoid alcohol consumption during and after treatment.
- Contact your doctor if you experience severe side effects or if your condition worsens.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.
Driving Precautions
Nitoxin may cause dizziness or visual disturbances. Exercise caution when driving or operating machinery until you know how it affects you.
Lifestyle Advice
- Maintain good hydration by drinking plenty of fluids.
- Ensure adequate rest to aid recovery.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Nitoxin Brand
Other medicines available under the same brand name
