Novin
Generic Name
Xylometazoline Hydrochloride
Manufacturer
PharmaCo Bangladesh Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| novin 01 nasal drop | ৳ 7.53 | N/A |
Description
Overview of the medicine
Novin-01 Nasal Drop contains Xylometazoline Hydrochloride, a topical decongestant that helps relieve nasal congestion associated with colds, allergies, and sinusitis.
Uses & Indications
Dosage
Adults
2-3 drops into each nostril, 2-3 times daily. Do not exceed 3 applications daily.
Elderly
Same as adult dosage, but use with caution in patients with underlying cardiovascular conditions.
Renal_impairment
No specific dosage adjustment required, minimal systemic absorption.
How to Take
For nasal use only. Blow your nose gently before applying. Tilt head back, apply drops into each nostril, and keep head tilted for a few moments.
Mechanism of Action
Xylometazoline is a sympathomimetic agent with alpha-adrenergic activity. It causes vasoconstriction of the nasal blood vessels, leading to a reduction in swelling and congestion.
Pharmacokinetics
Onset
5-10 minutes
Excretion
Primarily via local metabolism and insignificant systemic excretion.
Half life
Approximately 5-6 hours (local action)
Absorption
Minimal systemic absorption from nasal application.
Metabolism
Not extensively metabolized due to minimal systemic absorption.
Side Effects
Contraindications
- Hypersensitivity to xylometazoline or any component
- Transsphenoidal hypophysectomy or surgery exposing the dura mater
- Acute angle-closure glaucoma
- Rhinitis sicca (dry rhinitis)
- Concomitant use with MAO inhibitors or within 14 days of stopping them
Drug Interactions
Tricyclic Antidepressants
Potentiation of pressor effects.
Monoamine Oxidase Inhibitors (MAOIs)
Increased risk of hypertensive crisis.
Storage
Store below 30°C in a cool, dry place, away from direct sunlight. Do not freeze.
Overdose
Overdose may cause severe systemic effects, especially in children, including CNS depression, bradycardia, hypertension, and coma. Symptomatic and supportive treatment is necessary.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and under medical supervision. Consult your doctor before use.
Side Effects
Contraindications
- Hypersensitivity to xylometazoline or any component
- Transsphenoidal hypophysectomy or surgery exposing the dura mater
- Acute angle-closure glaucoma
- Rhinitis sicca (dry rhinitis)
- Concomitant use with MAO inhibitors or within 14 days of stopping them
Drug Interactions
Tricyclic Antidepressants
Potentiation of pressor effects.
Monoamine Oxidase Inhibitors (MAOIs)
Increased risk of hypertensive crisis.
Storage
Store below 30°C in a cool, dry place, away from direct sunlight. Do not freeze.
Overdose
Overdose may cause severe systemic effects, especially in children, including CNS depression, bradycardia, hypertension, and coma. Symptomatic and supportive treatment is necessary.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and under medical supervision. Consult your doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months. Refer to package for specific expiry date.
Availability
Pharmacies, drugstores
Approval Status
Approved
Patent Status
Generic
Clinical Trials
Extensively studied for efficacy and safety in relieving nasal congestion.
Lab Monitoring
- No specific lab monitoring required for typical use.
Doctor Notes
- Advise patients on short-term use only.
- Caution in patients with hypertension, hyperthyroidism, and diabetes.
- Not for use in infants without medical advice.
Patient Guidelines
- Do not use for more than 7 consecutive days to avoid rebound congestion.
- Avoid contact with eyes.
- Wash hands thoroughly after use.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
No known effects on ability to drive or operate machinery at recommended doses. However, if you experience side effects like dizziness, avoid driving.
Lifestyle Advice
- Maintain good hydration.
- Avoid irritants like smoke and dust.
- Consider a humidifier in dry environments.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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