Opdex
Generic Name
Omeprazole
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| opdex 03 01 eye drop | ৳ 75.00 | N/A |
Description
Overview of the medicine
Opdex (Omeprazole) is a proton pump inhibitor used to reduce the amount of acid produced in the stomach. It is commonly used to treat conditions such as heartburn, acid reflux, and stomach ulcers.
Uses & Indications
Dosage
Adults
GERD: 20-40 mg once daily for 4-8 weeks. Ulcers: 20-40 mg once daily for 4-8 weeks. Zollinger-Ellison: 60 mg once daily, adjusted as needed.
Elderly
No specific dose adjustment typically required, but caution in patients with hepatic impairment.
Renal_impairment
No dose adjustment necessary for renal impairment.
How to Take
Take orally, preferably in the morning before a meal. Swallow capsules whole; do not chew or crush.
Mechanism of Action
Omeprazole inhibits the H+/K+-ATPase (proton pump) in gastric parietal cells, thereby blocking the final step in acid production.
Pharmacokinetics
Onset
Within 1 hour, maximal effect within 2 hours
Excretion
Mainly excreted in urine (approximately 80%) and feces (approximately 20%) as metabolites.
Half life
0.5-1 hour (terminal half-life)
Absorption
Rapidly absorbed after oral administration, bioavailability is about 30-40% due to first-pass metabolism.
Metabolism
Extensively metabolized in the liver, primarily by CYP2C19 and CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to omeprazole or other benzimidazoles
- Concomitant use with nelfinavir
Drug Interactions
Warfarin
Increased INR/bleeding risk.
Nelfinavir
Significant reduction in nelfinavir exposure.
Clopidogrel
Reduced antiplatelet effect of clopidogrel.
Methotrexate
Increased methotrexate levels.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, dizziness, abdominal pain, diarrhea, headache. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Category C in pregnancy. Use only if potential benefit outweighs risk. Excreted in breast milk; caution advised.
Side Effects
Contraindications
- Hypersensitivity to omeprazole or other benzimidazoles
- Concomitant use with nelfinavir
Drug Interactions
Warfarin
Increased INR/bleeding risk.
Nelfinavir
Significant reduction in nelfinavir exposure.
Clopidogrel
Reduced antiplatelet effect of clopidogrel.
Methotrexate
Increased methotrexate levels.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, dizziness, abdominal pain, diarrhea, headache. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Category C in pregnancy. Use only if potential benefit outweighs risk. Excreted in breast milk; caution advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Available in all pharmacies in Bangladesh
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials support the efficacy and safety of omeprazole for its approved indications.
Doctor Notes
- Consider lowest effective dose for shortest duration. Review need for continued PPI therapy regularly.
- Educate patients on potential long-term risks.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose.
Driving Precautions
May cause dizziness or visual disturbances; exercise caution if affected.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Opdex Brand
Other medicines available under the same brand name
