Orgaflu
Generic Name
Orgafluvir 500 mg
Manufacturer
PharmaCo Bangladesh Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| orgaflu 500 mg capsule | ৳ 10.03 | ৳ 100.30 |
Description
Overview of the medicine
Orgaflu 500 mg Capsule is an antiviral medication used for the treatment and prophylaxis of influenza (flu) and other viral respiratory infections.
Uses & Indications
Dosage
Adults
For treatment: 500 mg orally twice daily for 5 days. For prophylaxis: 500 mg orally once daily for 10 days.
Elderly
No specific dose adjustment for elderly patients without renal impairment. Monitor renal function.
Renal_impairment
Dose reduction is necessary for patients with creatinine clearance < 30 mL/min; consult a physician for specific dosage.
How to Take
Orgaflu capsules can be taken orally with or without food. It is important to complete the full prescribed course of treatment.
Mechanism of Action
Orgafluvir inhibits the replication of various viruses by interfering with a key viral enzyme, thus preventing the spread of the virus within the body.
Pharmacokinetics
Onset
Therapeutic effects typically begin within 1-2 hours of administration.
Excretion
Mainly excreted via the renal pathway (kidneys).
Half life
Elimination half-life ranges from 6 to 10 hours.
Absorption
Rapid oral absorption after administration.
Metabolism
Primarily metabolized in the liver, often involving conversion of a prodrug to its active form.
Side Effects
Contraindications
- •Known hypersensitivity to Orgafluvir or any components of the capsule.
- •Severe hepatic impairment (use with caution and dose adjustment may be required).
Drug Interactions
Probenecid
Co-administration with probenecid may increase the systemic exposure to Orgafluvir. Monitor for adverse effects.
Live attenuated influenza vaccine
Concurrent use may reduce the efficacy of the live attenuated influenza vaccine. Administer vaccine at least 2 weeks before or 48 hours after Orgafluvir therapy.
Storage
Store in a cool, dry place below 30°C. Protect from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, supportive measures should be implemented. Gastric lavage may be considered if ingestion was recent. There is no specific antidote.
Pregnancy & Lactation
Use during pregnancy or lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or infant. Consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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