Oroxat

Take Oroxat 100 mg tablet orally, usually once daily in the morning, with or without food. Taking it with food may reduce gastrointestinal upset. Swallow the tablet whole; do not chew or crush it, especially if it is an extended-release formulation.

Paroxetine works by selectively inhibiting the reuptake of serotonin in the brain, thereby increasing the concentration of serotonin in the synaptic cleft. This leads to an enhancement of serotonergic neurotransmission, which helps to improve mood, reduce anxiety, and alleviate symptoms of various mental health disorders.

• Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing MAOI therapy.
• Concomitant use with thioridazine or pimozide due to increased risk of QT prolongation.
• Hypersensitivity to paroxetine or any component of the formulation.

Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.

Symptoms of overdose include somnolence, coma, nausea, vomiting, tremor, tachycardia, dizziness, and very rarely, seizures or serotonin syndrome. Management involves supportive care, maintaining an open airway, monitoring vital signs, and gastric lavage or activated charcoal if indicated. There is no specific antidote.

Pregnancy Category D: There is positive evidence of human fetal risk (particularly cardiac malformations, e.g., ventricular septal defects), but the benefits from use in pregnant women may be acceptable despite the risk. Not recommended during breastfeeding as paroxetine is excreted in breast milk and may cause adverse effects in the infant.

• Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing MAOI therapy.
• Concomitant use with thioridazine or pimozide due to increased risk of QT prolongation.
• Hypersensitivity to paroxetine or any component of the formulation.

Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.

Symptoms of overdose include somnolence, coma, nausea, vomiting, tremor, tachycardia, dizziness, and very rarely, seizures or serotonin syndrome. Management involves supportive care, maintaining an open airway, monitoring vital signs, and gastric lavage or activated charcoal if indicated. There is no specific antidote.

Pregnancy Category D: There is positive evidence of human fetal risk (particularly cardiac malformations, e.g., ventricular septal defects), but the benefits from use in pregnant women may be acceptable despite the risk. Not recommended during breastfeeding as paroxetine is excreted in breast milk and may cause adverse effects in the infant.