Oxigel
Generic Name
Benzoyl Peroxide
Manufacturer
Local/Generic Manufacturer
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
oxigel 25 topical gel | ৳ 150.00 | N/A |
Description
Overview of the medicine
Oxigel-25 Topical Gel is an antimicrobial and keratolytic agent used for the topical treatment of acne vulgaris. It works by reducing the amount of acne-causing bacteria and by causing the skin to dry and peel.
Uses & Indications
Dosage
Adults
Apply a thin layer to affected areas once or twice daily. Start with once daily and increase frequency if tolerated.
Elderly
Same as adults, with caution due to potentially thinner or more fragile skin.
Renal_impairment
No specific dosage adjustment required, as systemic absorption is minimal.
How to Take
For external use only. Wash and gently dry the affected skin before applying a thin layer of gel. Avoid contact with eyes, mouth, nose, and mucous membranes. Wash hands thoroughly after application.
Mechanism of Action
Benzoyl peroxide works in acne by killing bacteria (Propionibacterium acnes) on the skin and by causing the outer layer of the skin to shed (keratolytic effect). This helps to unplug blocked pores and prevents new pimples from forming.
Pharmacokinetics
Onset
Weeks for full therapeutic effect, but initial effects within days.
Excretion
Excreted as benzoic acid via urine if absorbed.
Half life
Not applicable for topical use due to minimal systemic absorption.
Absorption
Minimal systemic absorption through the skin; primarily acts locally.
Metabolism
Metabolized to benzoic acid in the skin and systemically if absorbed.
Side Effects
Contraindications
- Hypersensitivity to benzoyl peroxide or any component of the gel
- Application on broken or irritated skin
Drug Interactions
Dapsone topical
May cause temporary yellow/orange skin discoloration if applied simultaneously.
Tretinoin, Isoretinoin, Tazarotene
Concurrent use may cause excessive irritation and dryness. Apply at different times of day.
Storage
Store below 25°C, protected from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Topical overdose may result in severe irritation, redness, burning, and peeling. Discontinue use and apply cool compresses if irritation is severe. Systemic overdose is unlikely due to minimal absorption.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the benefit outweighs the potential risk. Caution is advised during lactation; avoid application to breast area to prevent infant exposure.
Side Effects
Contraindications
- Hypersensitivity to benzoyl peroxide or any component of the gel
- Application on broken or irritated skin
Drug Interactions
Dapsone topical
May cause temporary yellow/orange skin discoloration if applied simultaneously.
Tretinoin, Isoretinoin, Tazarotene
Concurrent use may cause excessive irritation and dryness. Apply at different times of day.
Storage
Store below 25°C, protected from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Topical overdose may result in severe irritation, redness, burning, and peeling. Discontinue use and apply cool compresses if irritation is severe. Systemic overdose is unlikely due to minimal absorption.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the benefit outweighs the potential risk. Caution is advised during lactation; avoid application to breast area to prevent infant exposure.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies, drugstores, online
Approval Status
Approved by DGDA
Patent Status
Generic/Off-patent
Clinical Trials
Extensively studied and proven effective for acne vulgaris. Ongoing research for formulation improvements.
Lab Monitoring
- No specific lab monitoring required for topical use.
Doctor Notes
- Advise patients on proper application technique and potential for skin irritation.
- Emphasize sun protection due to increased photosensitivity.
- Counsel on realistic expectations for treatment duration and outcome.
Patient Guidelines
- Perform a patch test before wide application to check for sensitivity.
- Avoid excessive sun exposure and use sunscreen.
- Do not apply on open wounds or mucous membranes.
- It may bleach hair or colored fabrics.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember, unless it is almost time for your next dose. Do not apply a double dose to make up for a missed one.
Driving Precautions
No known effects on ability to drive or operate machinery.
Lifestyle Advice
- Maintain a regular skincare routine.
- Avoid picking or squeezing pimples.
- Use non-comedogenic cleansers and moisturizers.
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Global Brand Names
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