Pol
Generic Name
Paracetamol 120 mg Suspension
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| pol 120 mg suspension | ৳ 35.00 | N/A |
Description
Overview of the medicine
Pol 120 mg Suspension contains Paracetamol, an effective analgesic and antipyretic used to relieve mild to moderate pain and reduce fever in children.
Uses & Indications
Dosage
Adults
Not recommended for adults in this strength. Adults typically take 500-1000 mg every 4-6 hours.
Elderly
Not recommended for elderly in this strength. Elderly typically take 500-1000 mg every 4-6 hours, adjust for renal function.
Renal_impairment
Dose interval prolongation may be necessary in severe renal impairment (e.g., 8 hours between doses for CrCl < 10 mL/min).
How to Take
Administer orally. Shake the bottle well before use. Use a measuring spoon or oral syringe to ensure accurate dosing, especially for children. May be taken with or without food.
Mechanism of Action
The exact mechanism is not fully understood, but it is believed to inhibit prostaglandin synthesis in the central nervous system, leading to its analgesic and antipyretic effects.
Pharmacokinetics
Onset
30 to 60 minutes
Excretion
Mainly excreted in the urine as glucuronide and sulfate conjugates. Less than 5% is excreted unchanged.
Half life
1 to 4 hours
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 30 to 60 minutes.
Metabolism
Primarily metabolized in the liver, mainly through glucuronidation and sulfation, with a small portion metabolized by cytochrome P450 to a toxic intermediate (NAPQI).
Side Effects
Contraindications
- Hypersensitivity to paracetamol or any component of the suspension
- Severe hepatic impairment
Drug Interactions
Alcohol
Increased risk of liver toxicity with chronic alcohol consumption.
Warfarin
May increase the anticoagulant effect of warfarin and other coumarins, leading to an increased risk of bleeding.
Certain anticonvulsants (e.g., carbamazepine, phenobarbital)
May increase the risk of hepatotoxicity.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Overdose can cause severe, potentially fatal liver damage. Symptoms may include nausea, vomiting, abdominal pain, and loss of appetite. Seek immediate medical attention even if feeling well.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation at recommended doses, but consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to paracetamol or any component of the suspension
- Severe hepatic impairment
Drug Interactions
Alcohol
Increased risk of liver toxicity with chronic alcohol consumption.
Warfarin
May increase the anticoagulant effect of warfarin and other coumarins, leading to an increased risk of bleeding.
Certain anticonvulsants (e.g., carbamazepine, phenobarbital)
May increase the risk of hepatotoxicity.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Overdose can cause severe, potentially fatal liver damage. Symptoms may include nausea, vomiting, abdominal pain, and loss of appetite. Seek immediate medical attention even if feeling well.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation at recommended doses, but consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (unopened)
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA/FDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Paracetamol has been extensively studied in numerous clinical trials establishing its efficacy and safety for pain and fever relief.
Lab Monitoring
- Liver function tests (in cases of overdose or prolonged high-dose therapy)
- Renal function tests (in cases of renal impairment)
Doctor Notes
- Educate parents/caregivers on proper dosing based on weight/age.
- Warn against concomitant use with other paracetamol products to avoid overdose.
- Advise on seeking medical attention for persistent symptoms or signs of liver damage.
Patient Guidelines
- Do not exceed the recommended dose.
- Do not use with other paracetamol-containing products.
- Consult a doctor if symptoms persist for more than 3 days (fever) or 5 days (pain).
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Pol 120 mg Suspension is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain adequate hydration.
- Rest during illness.
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Global Brand Names
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