ProAir
Generic Name
Albuterol Sulfate 10 mg Tablet
Manufacturer
Teva Respiratory, LLC (associated with ProAir brand)
Country
USA
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| proair 10 mg tablet | ৳ 14.00 | N/A |
Description
Overview of the medicine
ProAir is a brand name primarily for albuterol sulfate inhalation products. This entry refers to a hypothetical 10 mg oral tablet formulation of Albuterol Sulfate, a short-acting beta-agonist used to relieve bronchospasm in conditions like asthma and COPD.
Uses & Indications
Dosage
Adults
Standard oral albuterol tablets are usually 2 mg or 4 mg, taken 3-4 times daily. A 10 mg tablet would be an unusually high single dose and should only be taken as specifically directed by a physician for particular situations or as an extended-release formulation.
Elderly
Similar to adults, but dosage should be initiated at the lower end of the dosing range due to greater frequency of decreased hepatic, renal, or cardiac function, and concomitant disease or other drug therapy. A 10 mg dose may be too high for initial therapy.
Renal_impairment
Use with caution. Dosage adjustments may be necessary in severe renal impairment, as a significant portion is renally excreted.
How to Take
Take the tablet orally with water, with or without food, as directed by your doctor.
Mechanism of Action
Albuterol selectively stimulates beta-2 adrenergic receptors in the lungs, leading to relaxation of bronchial smooth muscle and bronchodilation.
Pharmacokinetics
Onset
Oral tablets typically have an onset of action within 30 minutes to 2 hours.
Excretion
Primarily excreted in the urine (80-100% within 24 hours), as unchanged drug and its metabolite.
Half life
Plasma half-life of oral albuterol is approximately 3.8 to 5 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract after oral administration. Bioavailability is approximately 50%.
Metabolism
Extensively metabolized in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- Hypersensitivity to albuterol or any component of the formulation.
- Severe milk protein allergy (for some inhaler formulations, not directly applicable to tablets but general caution for albuterol).
Drug Interactions
Digoxin
May decrease digoxin levels.
Diuretics (e.g., Furosemide)
May potentiate hypokalemia and ECG changes.
Beta-blockers (e.g., Propranolol)
Can block the bronchodilator effect of albuterol and produce severe bronchospasm.
MAO Inhibitors & Tricyclic Antidepressants
May potentiate the vascular effects of albuterol, increasing risk of cardiovascular adverse effects.
Storage
Store at controlled room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremor, nervousness, headache, dizziness, hypokalemia, hyperglycemia. Management involves symptomatic and supportive therapy. Cardioselective beta-blockers may be considered in severe cases, but with extreme caution due to risk of bronchospasm.
Pregnancy & Lactation
Pregnancy Category C (older classification): Use only if the potential benefit justifies the potential risk to the fetus. Albuterol is excreted in human breast milk; use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to albuterol or any component of the formulation.
- Severe milk protein allergy (for some inhaler formulations, not directly applicable to tablets but general caution for albuterol).
Drug Interactions
Digoxin
May decrease digoxin levels.
Diuretics (e.g., Furosemide)
May potentiate hypokalemia and ECG changes.
Beta-blockers (e.g., Propranolol)
Can block the bronchodilator effect of albuterol and produce severe bronchospasm.
MAO Inhibitors & Tricyclic Antidepressants
May potentiate the vascular effects of albuterol, increasing risk of cardiovascular adverse effects.
Storage
Store at controlled room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremor, nervousness, headache, dizziness, hypokalemia, hyperglycemia. Management involves symptomatic and supportive therapy. Cardioselective beta-blockers may be considered in severe cases, but with extreme caution due to risk of bronchospasm.
Pregnancy & Lactation
Pregnancy Category C (older classification): Use only if the potential benefit justifies the potential risk to the fetus. Albuterol is excreted in human breast milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date, or as indicated on packaging.
Availability
Pharmacies
Approval Status
FDA Approved (for Albuterol)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established the efficacy and safety of albuterol for bronchodilation. Specific trials for a 10 mg oral tablet are less common, as standard doses are lower.
Lab Monitoring
- Serum potassium levels (especially in patients with concomitant conditions or on other medications that can cause hypokalemia).
- Glucose levels (in diabetic patients).
Doctor Notes
- Note that 'ProAir' is predominantly known as a brand for albuterol inhalers (MDI, nebulizer solution). An oral 10 mg tablet of albuterol is an atypical and high dose, not a standard 'ProAir' product.
- If prescribing an albuterol 10 mg tablet, carefully consider the patient's condition, other medications, and potential for adverse effects, especially cardiovascular. Begin with lower doses of albuterol oral tablets (e.g., 2 mg or 4 mg) unless specific clinical need for a higher dose is justified.
Patient Guidelines
- Take exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Report any severe or persistent side effects to your doctor.
- This tablet formulation is distinct from ProAir inhalers; ensure you are taking the correct medication.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness, tremor, or nervousness. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Avoid smoking and exposure to respiratory irritants.
- Follow an asthma or COPD action plan, if provided.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in ProAir Brand
Other medicines available under the same brand name
