Probis-Plus
Generic Name
Probis-Plus 25 mg tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| probis plus 25 mg tablet | ৳ 6.02 | ৳ 60.20 |
Description
Overview of the medicine
Probis-Plus 25 mg tablet is a dietary supplement containing beneficial microorganisms (probiotics) intended to restore and maintain a healthy gut flora. It helps in improving digestion, boosting immunity, and alleviating various gastrointestinal issues.
Uses & Indications
Dosage
Adults
Typically, 1 tablet once or twice daily, or as directed by a healthcare professional.
Elderly
Same as adult dosage, no specific adjustment usually required.
Renal_impairment
No specific dosage adjustment required as it's not systemically absorbed.
How to Take
Take the tablet orally with water, preferably with a meal or as directed. Do not crush or chew the tablet unless specifically instructed.
Mechanism of Action
Probiotics work by introducing beneficial bacteria into the gut, which then colonize the intestinal tract. They compete with harmful bacteria for nutrients and adhesion sites, produce antimicrobial substances, modulate the immune system, and help in the digestion and absorption of nutrients. This helps in restoring the balance of gut microbiota.
Pharmacokinetics
Onset
Effects may be noticed within a few days to weeks, depending on the condition and individual response.
Excretion
Excreted primarily via feces.
Half life
Not applicable as live organisms, duration of colonization varies.
Absorption
Live microorganisms are not absorbed into the bloodstream but act locally within the gastrointestinal tract.
Metabolism
Undergo metabolic activity within the gut lumen, producing beneficial compounds (e.g., short-chain fatty acids).
Side Effects
Contraindications
- Known hypersensitivity to any component of the formulation
- Patients with severely compromised immune systems (e.g., organ transplant recipients, chemotherapy patients) - consult a doctor
- Short bowel syndrome (for some strains)
Drug Interactions
Antibiotics
Antibiotics can kill beneficial bacteria, so take probiotics at least 2-3 hours apart from antibiotic doses.
Immunosuppressants
Use with caution in immunocompromised patients; consult a doctor as there's a theoretical risk of infection.
Storage
Store in a cool, dry place below 25°C, away from direct sunlight and moisture. Do not freeze.
Overdose
Overdose is unlikely to cause severe adverse effects. High doses may lead to increased flatulence or mild gastrointestinal discomfort. Symptomatic treatment if necessary.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation, but always consult a healthcare professional before use.
Side Effects
Contraindications
- Known hypersensitivity to any component of the formulation
- Patients with severely compromised immune systems (e.g., organ transplant recipients, chemotherapy patients) - consult a doctor
- Short bowel syndrome (for some strains)
Drug Interactions
Antibiotics
Antibiotics can kill beneficial bacteria, so take probiotics at least 2-3 hours apart from antibiotic doses.
Immunosuppressants
Use with caution in immunocompromised patients; consult a doctor as there's a theoretical risk of infection.
Storage
Store in a cool, dry place below 25°C, away from direct sunlight and moisture. Do not freeze.
Overdose
Overdose is unlikely to cause severe adverse effects. High doses may lead to increased flatulence or mild gastrointestinal discomfort. Symptomatic treatment if necessary.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation, but always consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, online stores
Approval Status
Approved by DGDA
Patent Status
Generic/Off-patent
Clinical Trials
Numerous clinical trials support the efficacy of various probiotic strains for gut health, but specific trials for 'Probis-Plus 25 mg tablet' may vary.
Lab Monitoring
- No routine lab monitoring is required for probiotic use.
Doctor Notes
- Educate patients on proper storage to maintain viability of live cultures.
- Advise patients to report any unusual or severe gastrointestinal discomfort.
- Emphasize that probiotics are supplements and not a substitute for medical treatment.
Patient Guidelines
- Take regularly for best results.
- Store in a cool, dry place away from direct sunlight.
- Consult your doctor if symptoms persist or worsen.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose.
Driving Precautions
Probis-Plus is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fiber.
- Stay hydrated.
- Engage in regular physical activity.
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Global Brand Names
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