Pulmidone
Generic Name
Respirolast 267 mg
Manufacturer
Apex Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| pulmidone 267 mg tablet | ৳ 45.00 | ৳ 450.00 |
Description
Overview of the medicine
Pulmidone 267 mg Tablet is a combination medicine used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). It contains a long-acting bronchodilator and an anti-inflammatory corticosteroid.
Uses & Indications
Dosage
Adults
One tablet (267 mg) once daily, preferably at the same time each day.
Elderly
No dosage adjustment is generally required for elderly patients; however, caution is advised due to potential age-related organ function decline.
Renal_impairment
No specific dosage adjustment is required for patients with mild to moderate renal impairment. Use with caution in severe renal impairment.
How to Take
Take the tablet whole with a glass of water, with or without food. Do not crush, chew, or break the tablet.
Mechanism of Action
Respirolast, the active ingredient, works by relaxing the muscles in the airways, making them wider and easier to breathe through (bronchodilation), and by reducing inflammation in the lungs. This dual action helps to control symptoms like wheezing, shortness of breath, and coughing.
Pharmacokinetics
Onset
Bronchodilatory effect starts within 30-60 minutes.
Excretion
Excreted mainly through feces and urine as metabolites.
Half life
Approximately 12-15 hours.
Absorption
Rapidly absorbed after oral administration, with peak plasma concentrations achieved within 1-2 hours.
Metabolism
Primarily metabolized in the liver via CYP3A4 pathway.
Side Effects
Contraindications
- Hypersensitivity to Respirolast or any component of the tablet
- Acute bronchospasm or status asthmaticus
- Not for initial treatment of asthma or COPD
Drug Interactions
Diuretics
May increase the risk of hypokalemia.
Beta-blockers
May reduce the bronchodilatory effect of Respirolast.
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
May increase plasma levels of Respirolast, leading to increased risk of side effects.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include tachycardia, tremors, headache, and palpitations. Treatment is symptomatic and supportive. Monitor cardiac function and serum potassium levels.
Pregnancy & Lactation
Use in pregnancy only if the potential benefit outweighs the potential risk to the fetus. Consult your doctor. It is unknown if Respirolast is excreted in human milk; use with caution during lactation.
Side Effects
Contraindications
- Hypersensitivity to Respirolast or any component of the tablet
- Acute bronchospasm or status asthmaticus
- Not for initial treatment of asthma or COPD
Drug Interactions
Diuretics
May increase the risk of hypokalemia.
Beta-blockers
May reduce the bronchodilatory effect of Respirolast.
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
May increase plasma levels of Respirolast, leading to increased risk of side effects.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include tachycardia, tremors, headache, and palpitations. Treatment is symptomatic and supportive. Monitor cardiac function and serum potassium levels.
Pregnancy & Lactation
Use in pregnancy only if the potential benefit outweighs the potential risk to the fetus. Consult your doctor. It is unknown if Respirolast is excreted in human milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture
Availability
Available in pharmacies and hospitals nationwide
Approval Status
Approved by DGDA
Patent Status
Patent protected (expires 2035)
Clinical Trials
Ongoing phase IV trials are evaluating the long-term efficacy and safety in pediatric populations.
Lab Monitoring
- Regular pulmonary function tests (PFTs)
- Serum potassium levels (especially with concomitant diuretic use)
Doctor Notes
- Emphasize proper administration technique and adherence to daily dosing for optimal control.
- Educate patients on the difference between maintenance therapy and rescue medication.
- Monitor patients for cardiovascular side effects, especially in those with pre-existing conditions.
Patient Guidelines
- Do not stop taking Pulmidone suddenly without consulting your doctor.
- Always carry your rescue inhaler if prescribed for acute symptoms.
- Report any worsening of symptoms or severe side effects to your doctor immediately.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
May cause dizziness or tremors; caution is advised when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Avoid smoking and exposure to respiratory irritants.
- Regular exercise and a healthy diet can support lung health.
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Global Brand Names
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