Pulmoten
Generic Name
Indacaterol
Manufacturer
XYZ Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| pulmoten 6250 mg tablet | ৳ 50.00 | ৳ 500.00 |
Description
Overview of the medicine
Pulmoten is a long-acting beta2-adrenergic agonist (LABA) used for the maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD).
Uses & Indications
Dosage
Adults
For COPD, 75 mcg (or 150 mcg depending on brand/region) once daily via oral inhalation using the device.
Elderly
No dose adjustment required based on age.
Renal_impairment
No dose adjustment required in patients with renal impairment.
How to Take
Pulmoten capsules are for oral inhalation only and must be used with the specific inhaler device. Do not swallow the capsules.
Mechanism of Action
Indacaterol selectively stimulates beta2-adrenergic receptors in the lung, leading to relaxation of bronchial smooth muscle, resulting in bronchodilation. This effect helps to improve airflow in patients with COPD.
Pharmacokinetics
Onset
Within 5 minutes.
Excretion
Predominantly excreted via feces (94%), with a small amount (6%) excreted via urine.
Half life
Approximately 40-56 hours (terminal half-life).
Absorption
Rapidly absorbed after oral inhalation, peak plasma concentrations reached within 15-30 minutes.
Metabolism
Primarily metabolized by UGT1A1 and to a lesser extent by CYP3A4.
Side Effects
Contraindications
- Acute bronchospasm (not a rescue medication)
- Not for asthma (increased risk of asthma-related death)
- Hypersensitivity to Indacaterol or any excipients.
Drug Interactions
Diuretics
May increase risk of hypokalemia.
Beta-blockers
May reduce effect of Indacaterol.
Other sympathomimetic agents
May potentiate adverse effects.
Tricyclic antidepressants, MAO inhibitors
May potentiate cardiovascular effects.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include excessive beta-adrenergic stimulation (e.g., tachycardia, palpitations, arrhythmia, tremor, headache, nausea, vomiting, hypokalemia, hyperglycemia). Treatment is supportive and symptomatic.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is unknown if Indacaterol is excreted in human milk; caution is advised.
Side Effects
Contraindications
- Acute bronchospasm (not a rescue medication)
- Not for asthma (increased risk of asthma-related death)
- Hypersensitivity to Indacaterol or any excipients.
Drug Interactions
Diuretics
May increase risk of hypokalemia.
Beta-blockers
May reduce effect of Indacaterol.
Other sympathomimetic agents
May potentiate adverse effects.
Tricyclic antidepressants, MAO inhibitors
May potentiate cardiovascular effects.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include excessive beta-adrenergic stimulation (e.g., tachycardia, palpitations, arrhythmia, tremor, headache, nausea, vomiting, hypokalemia, hyperglycemia). Treatment is supportive and symptomatic.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is unknown if Indacaterol is excreted in human milk; caution is advised.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months when stored properly.
Availability
Pharmacies, hospitals
Approval Status
Approved by regulatory bodies for COPD
Patent Status
Patent protected (for original brand), generics available
Clinical Trials
Indacaterol has been extensively studied in clinical trials involving patients with COPD, demonstrating significant improvement in lung function and reduction in symptoms.
Lab Monitoring
- Monitor for signs of cardiovascular effects (e.g., ECG)
- Monitor serum potassium and glucose levels in susceptible patients.
Doctor Notes
- Emphasize proper inhalation technique to patients.
- Assess patient's overall cardiovascular risk profile before initiation.
- Not to be used as monotherapy for asthma.
Patient Guidelines
- Use only with the provided inhaler device.
- Do not swallow the capsules.
- Do not use for sudden breathing problems.
- Seek immediate medical attention if breathing worsens.
Missed Dose Advice
If a dose is missed, take it as soon as possible. If it's almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once.
Driving Precautions
May cause dizziness or visual disturbances. Patients should be cautious when driving or operating machinery until they know how Pulmoten affects them.
Lifestyle Advice
- Avoid smoking to improve COPD symptoms.
- Regular exercise and a healthy diet can support lung health.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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