Radex
Generic Name
Ranitidine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| radex 05 mg tablet | ৳ 5.00 | ৳ 50.00 |
Description
Overview of the medicine
Radex contains Ranitidine, a histamine H2-receptor antagonist used to decrease stomach acid production. It is used to treat and prevent stomach and duodenal ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome.
Uses & Indications
Dosage
Adults
For duodenal/gastric ulcer: 150 mg twice daily or 300 mg at bedtime. For GERD: 150 mg twice daily.
Elderly
No dose adjustment generally required unless renal impairment is present.
Renal_impairment
Dose reduction (e.g., 150 mg daily) is recommended if creatinine clearance is less than 50 mL/min.
How to Take
Can be taken with or without food. For bedtime dose, take after evening meal.
Mechanism of Action
Ranitidine selectively blocks histamine H2-receptors on the gastric parietal cells, leading to a reduction in both basal and stimulated gastric acid secretion.
Pharmacokinetics
Onset
Within 60 minutes
Excretion
Primarily excreted in urine as unchanged drug and metabolites.
Half life
2-3 hours
Absorption
Rapidly absorbed after oral administration; bioavailability about 50%.
Metabolism
Partially metabolized in the liver by oxidation, demethylation, and N-oxidation.
Side Effects
Contraindications
- •Hypersensitivity to Ranitidine or any component of the formulation
- •Acute porphyria
Drug Interactions
Warfarin
May affect prothrombin time; monitor INR.
Theophylline
May increase theophylline plasma levels.
Ketoconazole/Itraconazole
Reduced absorption due to increased gastric pH.
Atenolol, Metoprolol, Propranolol
May increase plasma concentrations of beta-blockers.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptomatic and supportive treatment. Gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category B. Use with caution during pregnancy if clearly needed. Excreted in breast milk; advise against use during lactation or monitor infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Available in pharmacies
Approval Status
Generally Approved
Patent Status
Patent expired
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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