Radivit-C
Generic Name
Ascorbic Acid (Vitamin C)
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| radivit c 1000 mg tablet | ৳ 16.00 | ৳ 256.00 |
Description
Overview of the medicine
Radivit-C is a vitamin C supplement essential for immune function, collagen formation, and as an antioxidant. It helps in the growth and repair of tissues, wound healing, and absorption of iron.
Uses & Indications
Dosage
Adults
500 mg once or twice daily, or as directed by a physician. For deficiency, higher doses may be used initially.
Elderly
Similar to adult dosage, no specific dosage adjustment is typically required.
Renal_impairment
Use with caution in patients with severe renal impairment due to the risk of oxalate stone formation with very high doses. Normal doses are generally safe.
How to Take
Oral administration. Can be taken with or without food. For chewable tablets, chew thoroughly before swallowing.
Mechanism of Action
Vitamin C acts as a cofactor in several enzymatic reactions, including those involved in collagen synthesis and neurotransmitter synthesis. It is a powerful antioxidant, protecting cells from damage by free radicals. It also plays a crucial role in immune cell function.
Pharmacokinetics
Onset
Rapid
Excretion
Primarily excreted unchanged or as metabolites in the urine. Excess amounts are rapidly excreted.
Half life
Approximately 10-20 days, depending on body stores and dose.
Absorption
Readily absorbed from the gastrointestinal tract, primarily in the small intestine, by an active transport mechanism. Absorption is dose-dependent.
Metabolism
Partially metabolized in the liver to inactive metabolites (e.g., oxalate).
Side Effects
Contraindications
- Hypersensitivity to ascorbic acid or any component of the formulation.
- Patients with hyperoxaluria or a history of oxalate kidney stones (especially with high doses).
- Hemochromatosis (iron overload)
Drug Interactions
Warfarin
High doses of Vitamin C may potentially interfere with the anticoagulant effect of warfarin. Monitor INR.
Deferoxamine
Increased iron toxicity when co-administered with high doses of Vitamin C in patients with iron overload.
Oral Contraceptives
May reduce plasma levels of Vitamin C, but typically not clinically significant.
Antacids containing Aluminum
May increase aluminum absorption. Avoid concurrent use in patients with renal impairment.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture.
Overdose
Symptoms of overdose may include gastrointestinal disturbances (e.g., nausea, diarrhea, abdominal cramps) and potentially increased risk of kidney stone formation with very high, chronic doses. Management is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation when taken at recommended daily allowances. For higher therapeutic doses, consult a physician.
Side Effects
Contraindications
- Hypersensitivity to ascorbic acid or any component of the formulation.
- Patients with hyperoxaluria or a history of oxalate kidney stones (especially with high doses).
- Hemochromatosis (iron overload)
Drug Interactions
Warfarin
High doses of Vitamin C may potentially interfere with the anticoagulant effect of warfarin. Monitor INR.
Deferoxamine
Increased iron toxicity when co-administered with high doses of Vitamin C in patients with iron overload.
Oral Contraceptives
May reduce plasma levels of Vitamin C, but typically not clinically significant.
Antacids containing Aluminum
May increase aluminum absorption. Avoid concurrent use in patients with renal impairment.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture.
Overdose
Symptoms of overdose may include gastrointestinal disturbances (e.g., nausea, diarrhea, abdominal cramps) and potentially increased risk of kidney stone formation with very high, chronic doses. Management is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation when taken at recommended daily allowances. For higher therapeutic doses, consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date
Availability
Pharmacies, Supermarkets
Approval Status
Approved (OTC)
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Ascorbic acid has been extensively studied for its roles in nutrition, immunity, and various disease states. Numerous clinical trials support its efficacy in treating and preventing scurvy, and its potential benefits in other conditions are ongoing research.
Lab Monitoring
- No routine lab monitoring is required for typical Vitamin C supplementation. In cases of severe deficiency or specific medical conditions, plasma or leukocyte ascorbate levels might be measured.
Doctor Notes
- Advise patients on appropriate dosage and potential interactions with other medications.
- Emphasize the importance of a balanced diet alongside supplementation.
- Counsel patients on the symptoms of hyperoxaluria if high doses are prescribed.
Patient Guidelines
- Do not exceed the recommended dose without consulting a healthcare professional.
- Store the medicine as directed.
- Keep out of reach of children.
- Inform your doctor about all medications and supplements you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Radivit-C is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits and vegetables to ensure adequate nutrient intake.
- Stay hydrated by drinking plenty of water.
- Engage in regular physical activity for overall health benefits.
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