Rasonix
Generic Name
Rabeprazole
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| rasonix 20 mg tablet | ৳ 7.00 | ৳ 70.00 |
Description
Overview of the medicine
Rabeprazole is a proton pump inhibitor used to reduce stomach acid, treating conditions like GERD, ulcers, and Zollinger-Ellison syndrome.
Uses & Indications
Dosage
Adults
GERD: 20 mg once daily for 4-8 weeks. PUD: 20 mg once daily for 4-8 weeks. Zollinger-Ellison: Initial 60 mg once daily, adjust as needed.
Elderly
No specific dosage adjustment usually needed, but caution advised.
Renal_impairment
No dosage adjustment.
How to Take
Take orally, preferably before a meal. Do not crush or chew the tablet.
Mechanism of Action
Selectively inhibits the H+/K+-ATPase enzyme system (proton pump) at the secretory surface of the gastric parietal cells, blocking the final step of acid production.
Pharmacokinetics
Onset
1 hour
Excretion
Urine (approx 90%) and feces.
Half life
1-2 hours
Absorption
Rapidly absorbed after oral administration, bioavailability about 52%.
Metabolism
Primarily hepatic, mainly via cytochrome P450 (CYP2C19 and CYP3A4).
Side Effects
Contraindications
- Hypersensitivity to Rabeprazole or other PPIs.
Drug Interactions
Digoxin
Increased digoxin levels.
Warfarin
Increased INR and prothrombin time.
Clopidogrel
Reduced effectiveness of Clopidogrel (though less significant than Omeprazole).
Methotrexate
Increased methotrexate levels, especially high dose.
Storage
Store below 30°C in a dry place, away from light.
Overdose
Symptomatic and supportive treatment. Rabeprazole is not dialyzable.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Avoid during lactation.
Side Effects
Contraindications
- Hypersensitivity to Rabeprazole or other PPIs.
Drug Interactions
Digoxin
Increased digoxin levels.
Warfarin
Increased INR and prothrombin time.
Clopidogrel
Reduced effectiveness of Clopidogrel (though less significant than Omeprazole).
Methotrexate
Increased methotrexate levels, especially high dose.
Storage
Store below 30°C in a dry place, away from light.
Overdose
Symptomatic and supportive treatment. Rabeprazole is not dialyzable.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Avoid during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Information available in medical literature regarding Rabeprazole's efficacy and safety.
Lab Monitoring
- Liver function tests (if liver impairment)
- Magnesium levels (long-term use)
Doctor Notes
- Educate patients on the proper administration (whole, before food).
- Consider calcium and vitamin D supplementation for long-term PPI users.
Patient Guidelines
- Complete the full course of medication.
- Report any severe side effects to your doctor.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
May cause dizziness; avoid driving or operating machinery if affected.
Lifestyle Advice
- Avoid trigger foods for GERD (spicy, fatty, acidic foods).
- Elevate head during sleep.
- Quit smoking and reduce alcohol intake.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Rasonix Brand
Other medicines available under the same brand name
