Relise 100 mg Tablet should be taken orally, preferably with food or milk, to minimize gastrointestinal discomfort. Do not chew or crush the tablet; swallow it whole with a glass of water.

Myofenac, a potent NSAID, inhibits the activity of cyclooxygenase (COX) enzymes, primarily COX-2, which are responsible for the synthesis of prostaglandins. Prostaglandins are mediators of inflammation, pain, and fever. By inhibiting their synthesis, Myofenac reduces these symptoms.

• •Hypersensitivity to Myofenac or other NSAIDs (e.g., aspirin, ibuprofen)
• •Active gastrointestinal bleeding or peptic ulcer
• •Severe heart failure (NYHA Class II-IV)
• •Severe renal or hepatic impairment
• •Third trimester of pregnancy

Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose may include drowsiness, nausea, vomiting, epigastric pain, gastrointestinal bleeding, and rarely, acute renal failure, respiratory depression, and coma. Treatment is symptomatic and supportive, including gastric lavage or activated charcoal if ingestion is recent. Monitor renal function and electrolyte balance.

Relise is contraindicated in the third trimester of pregnancy due to the risk of premature closure of the ductus arteriosus and fetal renal dysfunction. In the first and second trimesters, it should be used only if the potential benefit justifies the potential risk to the fetus. It is not recommended during breastfeeding as NSAIDs can be excreted in breast milk.