Remathrin
Generic Name
Remadacine Hydrochloride
Manufacturer
PharmaGlobal Inc.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| remathrin 5 w cream | ৳ 40.50 | N/A |
Description
Overview of the medicine
Remathrin is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever.
Uses & Indications
Dosage
Adults
50 mg orally twice daily, or as directed by physician.
Elderly
Lower doses may be required, close monitoring for adverse effects.
Renal_impairment
Dose adjustment necessary; consult physician.
How to Take
Take orally with food or milk to minimize gastrointestinal upset.
Mechanism of Action
Remadacine acts by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of pain and inflammation.
Pharmacokinetics
Onset
Onset of action typically within 30-60 minutes.
Excretion
Excreted mainly through the kidneys.
Half life
Elimination half-life ranges from 4 to 6 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to Remadacine or other NSAIDs
- Active gastrointestinal bleeding or ulceration
- Severe renal or hepatic impairment
- Last trimester of pregnancy
Drug Interactions
Warfarin
Increased risk of bleeding.
Diuretics
Reduced diuretic and antihypertensive effects.
ACE Inhibitors
Reduced antihypertensive effect and increased risk of renal impairment.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptomatic and supportive treatment. Gastric lavage or activated charcoal may be considered if ingested recently.
Pregnancy & Lactation
Avoid during the last trimester of pregnancy. Use with caution during lactation; consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patent Pending
Clinical Trials
Phase III clinical trials demonstrated efficacy in reducing pain and inflammation with a comparable safety profile to existing NSAIDs.
Lab Monitoring
- Monitor renal function (creatinine, BUN)
- Monitor liver enzymes (ALT, AST)
- Periodic complete blood count (CBC)
Doctor Notes
- Advise patients about potential GI and CV risks.
- Consider proton pump inhibitors for patients at high risk of GI adverse events.
- Regularly assess renal function and blood pressure during prolonged treatment.
Patient Guidelines
- Take the medicine exactly as prescribed.
- Report any unusual bleeding, black stools, or severe abdominal pain immediately.
- Do not take other NSAIDs concurrently without consulting your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Remathrin may cause dizziness or drowsiness in some individuals; avoid driving or operating heavy machinery until you know how it affects you.
Lifestyle Advice
- Avoid excessive alcohol consumption while on Remathrin.
- Stay adequately hydrated, especially in hot weather.
- Engage in light exercise to manage chronic pain, if applicable.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.