Respira
Generic Name
Salbutamol 2 mg Tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| respira 2 mg tablet | ৳ 1.70 | ৳ 17.00 |
Description
Overview of the medicine
Respira 2 mg Tablet contains Salbutamol, a selective beta-2 adrenoceptor agonist. It is used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD) such as wheezing and shortness of breath.
Uses & Indications
Dosage
Adults
Oral: 2-4 mg three or four times daily. Doses should be spaced to allow at least 6 hours between doses.
Elderly
Elderly patients may start with a lower dose (e.g., 2 mg three or four times daily) and adjust according to response and tolerability.
Renal_impairment
No specific dose adjustment is generally required, but caution is advised in severe renal impairment. Monitor for side effects.
How to Take
Take the tablet orally with water, with or without food, as directed by your doctor. Do not crush or chew the tablet.
Mechanism of Action
Salbutamol stimulates beta-2 adrenergic receptors in the bronchial smooth muscle, leading to relaxation of the smooth muscle and bronchodilation. This helps to open the airways, making breathing easier.
Pharmacokinetics
Onset
Oral onset: 30 minutes.
Excretion
Excreted primarily in the urine, both as unchanged drug and as the sulfate conjugate.
Half life
4-6 hours.
Absorption
Well absorbed from the gastrointestinal tract following oral administration. Peak plasma concentrations are reached within 2-3 hours.
Metabolism
Undergoes metabolism in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- Hypersensitivity to Salbutamol or any component of the tablet.
- Uncontrolled hyperthyroidism.
Drug Interactions
Digoxin
May increase serum digoxin levels.
Diuretics
Increased risk of hypokalemia with concomitant use of non-potassium-sparing diuretics.
Beta-blockers (e.g., Propranolol)
Can antagonize the effects of Salbutamol and may cause severe bronchospasm in asthmatic patients.
MAOIs and Tricyclic Antidepressants
May potentiate the vascular effects of Salbutamol, increasing risk of cardiovascular side effects.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include tachycardia, tremor, headache, and hypokalemia. Management involves symptomatic and supportive treatment, often including discontinuation of the drug and potassium supplementation if necessary.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Salbutamol is excreted in human milk; use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to Salbutamol or any component of the tablet.
- Uncontrolled hyperthyroidism.
Drug Interactions
Digoxin
May increase serum digoxin levels.
Diuretics
Increased risk of hypokalemia with concomitant use of non-potassium-sparing diuretics.
Beta-blockers (e.g., Propranolol)
Can antagonize the effects of Salbutamol and may cause severe bronchospasm in asthmatic patients.
MAOIs and Tricyclic Antidepressants
May potentiate the vascular effects of Salbutamol, increasing risk of cardiovascular side effects.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include tachycardia, tremor, headache, and hypokalemia. Management involves symptomatic and supportive treatment, often including discontinuation of the drug and potassium supplementation if necessary.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Salbutamol is excreted in human milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 to 3 years from the date of manufacture when stored under recommended conditions.
Availability
Available in pharmacies, hospitals, and clinics.
Approval Status
Approved by regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have established the efficacy and safety of Salbutamol in the management of reversible obstructive airway diseases across various age groups.
Lab Monitoring
- Monitor serum potassium levels, especially in patients receiving high doses or concomitant diuretics.
- Monitor blood glucose levels in diabetic patients.
Doctor Notes
- Advise patients to always carry their reliever inhaler.
- Monitor for cardiovascular side effects, especially in patients with pre-existing heart conditions.
- Assess overall asthma/COPD control to ensure oral Salbutamol is used appropriately as part of a treatment plan.
- Educate patients on the difference between rescue medication and maintenance medication.
Patient Guidelines
- Follow your doctor's instructions carefully regarding dosage and frequency.
- Do not exceed the prescribed dose without consulting your doctor.
- Carry your rescue inhaler at all times if you have asthma.
- Seek immediate medical attention if your breathing worsens or if you experience severe side effects.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Respira 2 mg Tablet may cause tremor or dizziness in some patients. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Avoid known triggers for your asthma or COPD, such as smoke, allergens, and pollutants.
- Maintain good hydration.
- Engage in regular, moderate exercise as tolerated to improve lung function.
- Quit smoking if you are a smoker.
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