Rinzin
Generic Name
Cetirizine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| rinzin 10 mg tablet | ৳ 3.00 | N/A |
Description
Overview of the medicine
Rinzin (Cetirizine Hydrochloride) is an antihistamine used for relief from allergy symptoms such as runny nose, sneezing, itching, and watery eyes. It is also used to treat hives and itching.
Uses & Indications
Dosage
Adults
10 mg once daily, or 5 mg twice daily.
Elderly
Reduced dosage may be required (e.g., 5 mg once daily).
Renal_impairment
Dosage adjustment needed (e.g., 5 mg once daily for moderate impairment).
How to Take
May be taken with or without food. Swallow the tablet whole with a glass of water.
Mechanism of Action
Cetirizine is a potent, selective H1-receptor antagonist. It works by blocking histamine, a natural substance that the body produces during an allergic reaction.
Pharmacokinetics
Onset
20-60 minutes
Excretion
Primarily excreted unchanged in the urine.
Half life
Approximately 8-12 hours
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached within 1 hour.
Metabolism
Minimal hepatic metabolism, primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to cetirizine, hydroxyzine, or any piperazine derivative.
- Severe renal impairment (creatinine clearance less than 10 mL/min).
Drug Interactions
Alcohol
May enhance CNS depressant effects.
CNS Depressants (e.g., sedatives, tranquilizers)
May increase drowsiness and impaired performance.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, agitation, and restlessness. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk, caution advised during lactation.
Side Effects
Contraindications
- Hypersensitivity to cetirizine, hydroxyzine, or any piperazine derivative.
- Severe renal impairment (creatinine clearance less than 10 mL/min).
Drug Interactions
Alcohol
May enhance CNS depressant effects.
CNS Depressants (e.g., sedatives, tranquilizers)
May increase drowsiness and impaired performance.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, agitation, and restlessness. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk, caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date
Availability
Available in all pharmacies and hospitals
Approval Status
Approved by DGDA
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Extensively studied in numerous clinical trials demonstrating efficacy and safety in various allergic conditions.
Lab Monitoring
- Generally not required. Liver and kidney function tests may be considered in patients with pre-existing conditions or prolonged use.
- No routine lab monitoring is needed.
Doctor Notes
- Advise patients regarding potential drowsiness.
- Consider reduced dose in elderly and renal impaired patients.
- Counsel on avoiding concomitant alcohol use.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- Avoid alcohol while taking this medicine as it may increase drowsiness.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
May cause drowsiness or dizziness, especially initially. Avoid driving or operating heavy machinery until you know how this medicine affects you.
Lifestyle Advice
- Identify and avoid known allergens.
- Keep your home clean to reduce dust mites.
- Avoid smoking and exposure to secondhand smoke.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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