Rizin 10 mg tablet should be taken orally, with or without food. It can be taken at any time of day, but typically once daily.

Cetirizine is a potent and selective antagonist of peripheral H1 receptors. It inhibits the histamine-mediated effects such as vasodilation, increased vascular permeability, and itching, without significantly crossing the blood-brain barrier.

• •Hypersensitivity to cetirizine, hydroxyzine, or any piperazine derivative
• •Patients with severe renal impairment (creatinine clearance <10 mL/min)

Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose may include drowsiness, tachycardia, tremor, headache, and urinary retention. Management is symptomatic and supportive; there is no specific antidote. Gastric lavage may be considered soon after ingestion.

Pregnancy Category B. Use only if clearly needed. Cetirizine is excreted in breast milk; caution should be exercised when administered to a nursing woman.