Roxiquin
Generic Name
Roxithromycin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| roxiquin 200 mg tablet | ৳ 12.00 | ৳ 120.00 |
Description
Overview of the medicine
Roxiquin is a macrolide antibiotic used to treat various bacterial infections including respiratory tract infections, skin and soft tissue infections, and certain genitourinary infections.
Uses & Indications
Dosage
Adults
For adults, the usual dosage is 150 mg twice daily or 300 mg once daily, taken before meals. Treatment duration typically ranges from 5 to 10 days, depending on the infection.
Elderly
No specific dose adjustment is generally required for elderly patients, unless there is severe renal or hepatic impairment.
Renal_impairment
No dose adjustment is needed for mild to moderate renal impairment. Caution is advised in severe renal impairment; a reduced dose may be considered.
How to Take
Roxiquin tablets should be taken orally, preferably before meals (at least 15 minutes before food) with a glass of water, to optimize absorption.
Mechanism of Action
Roxithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thus preventing the growth and multiplication of susceptible bacteria.
Pharmacokinetics
Onset
Peak plasma concentrations are usually reached within 1-2 hours after administration.
Excretion
Primarily excreted via bile and feces (about 50%), with a small amount (less than 10%) excreted in urine.
Half life
The elimination half-life is approximately 10-12 hours.
Absorption
Well absorbed orally, but absorption may be decreased by food. Bioavailability is approximately 50%.
Metabolism
Partially metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to roxithromycin, other macrolides, or any excipients of the product.
- •Co-administration with ergot alkaloids (e.g., ergotamine, dihydroergotamine) due to risk of severe vasoconstriction.
- •Co-administration with cisapride, pimozide, or terfenadine.
- •Severe hepatic impairment.
Drug Interactions
Digoxin
May increase plasma concentrations of digoxin, necessitating monitoring of digoxin levels.
Warfarin
May potentiate the anticoagulant effect of warfarin, requiring INR monitoring and dose adjustment.
Midazolam
May enhance the effects of midazolam and other benzodiazepines.
Theophylline
May increase theophylline levels, requiring therapeutic drug monitoring.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In cases of overdose, symptomatic and supportive treatment should be initiated. Gastric lavage and general supportive measures may be helpful. There is no specific antidote.
Pregnancy & Lactation
Pregnancy: Use Roxiquin during pregnancy only if clearly needed and the potential benefits outweigh the potential risks to the fetus. Consult a doctor. Lactation: Roxithromycin is excreted in breast milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture when stored under recommended conditions.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patent expired
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in
