rupoma
Generic Name
rupoma-10-mg-tablet
Manufacturer
PharmaCorp Bangladesh Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| rupoma 10 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Rupatadine is a non-sedating, long-acting antihistamine with selective peripheral H1-receptor antagonist activity. It is used to treat allergic rhinitis and urticaria in adults and adolescents (12 years and above).
Uses & Indications
Dosage
Adults
10 mg once daily.
Elderly
No special dosage adjustment is usually required, but caution should be exercised in patients with renal or hepatic impairment.
Renal_impairment
Caution, dose adjustment may be necessary in severe cases. Not recommended for patients with severe renal impairment without medical consultation.
How to Take
For oral use. Can be taken with or without food.
Mechanism of Action
Rupatadine acts as a selective peripheral H1-receptor antagonist. It also has antagonist activity against platelet-activating factor (PAF) and inhibits mast cell degranulation and release of inflammatory mediators.
Pharmacokinetics
Onset
Within 1 hour.
Excretion
Mainly via feces (60.9%) and urine (34.6%) as metabolites.
Half life
Approximately 5.9 hours (parent drug).
Absorption
Rapidly absorbed after oral administration. Tmax is approximately 0.75-1.5 hours.
Metabolism
Extensively metabolized by the liver via the cytochrome P450 (CYP3A4) pathway.
Side Effects
Contraindications
- •Hypersensitivity to rupatadine or any excipients of the tablet.
Drug Interactions
Grapefruit Juice
May increase rupatadine exposure.
Ketoconazole and Erythromycin
Can increase systemic exposure to rupatadine due to CYP3A4 inhibition.
CNS Depressants (e.g., Alcohol)
May enhance central nervous system effects, leading to increased drowsiness.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated. No specific antidote is known.
Pregnancy & Lactation
Pregnancy Category B. Use during pregnancy only if clearly needed after a thorough risk-benefit assessment. Not recommended during breastfeeding as it may be excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date. Refer to the packaging for the exact expiry date.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Off-patent in many regions
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Global Brand Names
International brand names for this medicine
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