Sapox
Generic Name
Cefuroxime Axetil
Manufacturer
Popular Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sapox 500 mg capsule | ৳ 6.78 | ৳ 67.80 |
Description
Overview of the medicine
Cefuroxime Axetil is a broad-spectrum cephalosporin antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
500 mg orally twice daily for 5-10 days depending on the infection.
Elderly
No specific dose adjustment is required unless there is significant renal impairment.
Renal_impairment
Dose adjustment required for creatinine clearance < 30 mL/min.
How to Take
Should be taken with food for optimal absorption.
Mechanism of Action
Cefuroxime axetil is a bactericidal agent that acts by inhibiting bacterial cell wall synthesis.
Pharmacokinetics
Onset
1-2 hours
Excretion
Renal excretion via glomerular filtration and tubular secretion.
Half life
Approximately 1.2 to 1.5 hours
Absorption
Rapidly absorbed and hydrolyzed to cefuroxime in the intestinal mucosa and blood.
Metabolism
Not metabolized; primarily excreted unchanged.
Side Effects
Contraindications
- Known hypersensitivity to cephalosporin antibiotics or any component of the formulation.
- History of severe hypersensitivity reaction to any other type of beta-lactam antibiotic (e.g., penicillins).
Drug Interactions
Probenecid
Increases cefuroxime plasma concentrations.
Oral Contraceptives
May reduce efficacy of oral contraceptives (advise additional contraception).
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include cerebral irritation leading to convulsions. Management includes supportive care and hemodialysis.
Pregnancy & Lactation
Category B for pregnancy. Use with caution during lactation; excreted in breast milk in small amounts.
Side Effects
Contraindications
- Known hypersensitivity to cephalosporin antibiotics or any component of the formulation.
- History of severe hypersensitivity reaction to any other type of beta-lactam antibiotic (e.g., penicillins).
Drug Interactions
Probenecid
Increases cefuroxime plasma concentrations.
Oral Contraceptives
May reduce efficacy of oral contraceptives (advise additional contraception).
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include cerebral irritation leading to convulsions. Management includes supportive care and hemodialysis.
Pregnancy & Lactation
Category B for pregnancy. Use with caution during lactation; excreted in breast milk in small amounts.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensively studied and clinically proven for its efficacy and safety in bacterial infections.
Lab Monitoring
- Renal function tests (for prolonged therapy or renal impairment)
- Liver function tests (if clinically indicated)
- CBC (for prolonged therapy)
Doctor Notes
- Confirm bacterial infection before prescribing.
- Monitor for signs of superinfection.
- Adjust dose in severe renal impairment.
Patient Guidelines
- Take the full course of medicine as prescribed, even if you feel better.
- Take with food.
- Do not share your medicine with others.
- Inform your doctor about any allergies or other medications you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose.
Driving Precautions
May cause dizziness; caution advised.
Lifestyle Advice
- Maintain good hygiene to prevent further infections.
- Stay hydrated.
- Avoid alcohol during antibiotic treatment.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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